ObjectiveEvaluate the impact of peritoneal dialysis catheter (PDC) tail‐end design variations on PDC‐related complications.MethodEffective data were extracted from databases. The literature was evaluated according to the Cochrane Handbook for Systematic Reviews of Interventions, and a meta‐analysis was conducted.ResultsAnalysis revealed that the straight‐tailed catheter was superior to the curled‐tailed catheter in minimizing catheter displacement and complication‐induced catheter removal (RR = 1.73, 95%CI:1.18–2.53, p = 0.005). In terms of complication‐induced PDC removal, the straight‐tailed catheter was superior to the curled‐tailed catheter (RR = 1.55, 95%CI: 1.15–2.08, p = 0.004).ConclusionCurled‐tail design of the catheter increased the risk of catheter displacement and complication‐induced catheter removal, whereas the straight‐tailed catheter was superior to the curled‐tailed catheter in terms of reducing catheter displacement and complication‐induced catheter removal. However, the analysis and comparison of factors such as leakage, peritonitis, exit‐site infection, and tunnel infection did not reveal a statistically significant difference between the two designs.