Peritoneal reaction resulting from iodinated contrast material: comparative study.

Abstract

A consensus does not exist as to the optimal contrast agent for hysterosalpingography. This study was undertaken to evaluate the early and delayed inflammatory responses of the peritoneal surfaces to various types of iodinated contrast media. Guinea pigs received intraperitoneal injections of lactated Ringer solution, iothalamate meglumine, diatrizoate sodium, ioxilan, or ethiodized oil. The inflammatory response of the peritoneal surfaces was assessed at 1,7, and 30 days. Five animals were studied at each time point for each agent. No animals that received Ringer lactate or iothalamate meglumine had inflammation at any time. Ioxilan produced inflammation in two of five animals at 7 days and no inflammation at 1 or 30 days. Ethiodized oil produced no inflammation at 1 day; however, three animals had inflammation at 7 days, and all five had inflammation at 30 days. The 30-day group showed striking inflammatory response with granulomatous features. The authors recommend the continued use of meglumine-based water-soluble ionic contrast material for hysterosalpingography.

Severe Transient Leukopenia following Hysterosalpingography

“…Water-based agents are preferred for hysterosalpingogram as they cause less peritoneal inflammation than oilbased agents [5] .…”

Prolonged lymphatic leak after retroperitoneal lymph node dissection: a case report

“…However, insertion of an abdominal drain was eventually required to relieve abdominal compartment syndrome. The use of Conray in this case was not effective or justified as it is water-soluble and does not promote significant peritoneal fibrosis [11]. The potential for serious deterioration with this postoperative complication was demonstrated with requirement for ventilation and subsequent foot drop in this patient.…”

Postoperative granulomatous peritonitis mimicking abdominal tuberculosis

“…In rare cases, granulomatous peritonitis can be caused by foreign material contamination during surgery . Peritonitis can be triggered by surgical glove powder, undigested particles from accidental intestinal perforation, cotton lint from disposable surgical drapes, and laparotomy pads or chemical antiseptics, which are used for peritoneal lavage, and it is then called postoperative granulomatous peritonitis …”

“…1,2 Peritonitis can be triggered by surgical glove powder, undigested particles from accidental intestinal perforation, cotton lint from disposable surgical drapes, and laparotomy pads or chemical antiseptics, which are used for peritoneal lavage, and it is then called postoperative granulomatous peritonitis. 1,[5][6][7][8][9] The true extent of postoperative granulomatous peritonitis is unknown.…”