Peritubular Hypercalcified Zone of Mammalian Dentin

Shimoyama, Taketeru

doi:10.1679/aohc1950.28.113

Cited by 6 publications

(5 citation statements)

References 11 publications

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“…However, many investigators are inclined to the view that as compared with those of root dentin the dentinal tubules of crown dentin is more apt to undergo calcification. This has been showed by ISOKAWA and SHIMOYAMA [6,7] with the teeth of several mammals. Therefore, no peritubular hypercalcified zones are often found in that part of dentin which is around the root canal.…”

Section: Discussionsupporting

confidence: 57%

Some Historadiographs of Human Dentin Structures

Isokawa

Satomura

Misu

et al. 1966

The Journal of Nihon University School of Dentistry

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Section: Discussionsupporting

confidence: 57%

Some Historadiographs of Human Dentin Structures

Isokawa

Satomura

Misu

et al. 1966

The Journal of Nihon University School of Dentistry

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“…Peritubular dentin is present in some of the animal teeth but not in others [18]. Shimoyama [19] studied the peritubular dentin of dogs by microradiography, confirming its presence without defining the regional relationship of dentin. In the observation of dog dentin by the author using SEM, peritubular dentin was present in the mantle dentin but not in the circumpulpal dentin.…”

Section: Discussionmentioning

confidence: 99%

Scanning Electron Microscopic Studies of the Peritubular Dentin in Dogs

Toda

Shimauchi

Takagi

et al. 1975

The Journal of Nihon University School of Dentistry

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“…The microstructure changes of enamel and dentin can also reflect mammalian feeding adaptations. For example, enamel rods, the basic unit of enamel, are rectangular in sheep and rabbits (herbivorous), columniform in dogs (carnivorous), and intermediate in humans (omnivorous) (Bradford 1967;Shimoyama 1967;Hua 2015).…”

Section: Introductionmentioning

confidence: 99%

Molecular Evolution of Tooth-Related Genes Provides New Insights into Dietary Adaptations of Mammals

et al. 2021

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Mammals have evolved different tooth phenotypes that are hypothesized to be associated with feeding habits. However, the genetic basis for the linkage has not been well explored. In this study, we investigated 13 tooth-related genes, including seven enamel-related genes (AMELX, AMBN, ENAM, AMTN, ODAM, KLK4 and MMP20) and six dentin-related genes (DSPP, COL1A1, DMP1, IBSP, MEPE and SPP1), from 63 mammals to determine their evolutionary history. Our results showed that different evolutionary histories have evolved among divergent feeding habits in mammals. There was stronger positive selection for eight genes (ENAM, AMTN, ODAM, KLK4, DSPP, DMP1, COL1A1, MEPE) in herbivore lineages. In addition, AMELX, AMBN, ENAM, AMTN, MMP20 and COL1A1 underwent accelerated evolution in herbivores. While relatively strong positive selection was detected in IBSP, SPP1, and DSPP, accelerated evolution was only detected for MEPE and SPP1 genes among the carnivorous lineages. We found positive selection on AMBN and ENAM genes for omnivorous primates in the catarrhini clade. Interestingly, a significantly positive association between the evolutionary rate of ENAM, ODAM, KLK4, MMP20 and the average enamel thickness was found in primates. Additionally, we found molecular convergence in some amino acid sites of tooth-related genes among the lineages whose feeding habit are similar. The positive selection of related genes might promote the formation and bio-mineralization of tooth enamel and dentin, which would make the tooth structure stronger. Our results revealed that mammalian tooth-related genes have experienced variable evolutionary histories, which provide some new insights into the molecular basis of dietary adaptation in mammals.

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Peritubular Hypercalcified Zone of Mammalian Dentin

Cited by 6 publications

References 11 publications

Some Historadiographs of Human Dentin Structures

Some Historadiographs of Human Dentin Structures

Scanning Electron Microscopic Studies of the Peritubular Dentin in Dogs

Molecular Evolution of Tooth-Related Genes Provides New Insights into Dietary Adaptations of Mammals

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