Permeability of porous gelcast scaffolds for bone tissue engineering

Innocentini, M. D. M.; Faleiros, R. K.; Pisani, Reinaldo; Thijs, Ivo; Luyten, Jan; Mullens, Steven

doi:10.1007/s10934-009-9331-2

Cited by 67 publications

(49 citation statements)

References 46 publications

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“…properties, there are other macrostructural requirements to allow cell seeding and migration throughout the scaffolds, such as high porosity level and pore size [5]. The pores are requested to be interconnected to maintain the vascular system required for continuing bone development, and larger than 100 µm [2].…”

Section: Introductionmentioning

confidence: 99%

“…In addition, Dhara&Bhargava [11] used ovalbumin from freshly extracted egg white to produce both Al 2 O 3 foams and Aluminum foams with M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT 4 porosities up to 95 vol.% and 45 vol.%, respectively. In [5], titanium foams were produced via gelcasting using a water-based powder suspension, where agar agar was used as gelling agent and Tergitol ™ as foaming agent. The foams possessed a porosity ranging from 70 to 80 vol.%.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Ovalbumin as foaming agent for Ti6Al4V foams produced by gelcasting

Biasetto

Moraes

Colombo

et al. 2016

Journal of Alloys and Compounds

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Ovalbumin as foaming agent for Ti6Al4V foams produced by gelcasting

Biasetto

Moraes

Colombo

et al. 2016

Journal of Alloys and Compounds

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“…4 and Table 2). The results depended on the direction of the air flow compared to the direction of the sample because permeability is inversely proportional to tortuosity [41]. In all samples, permeability was higher in the axial direction because for a given air velocity, radial samples showed a greater pressure drop.…”

Section: Microstructure Dependencementioning

confidence: 94%

Permeability and mechanical integrity of porous biomorphic SiC ceramics for application as hot-gas filters

et al. 2016

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Biomorphic SiC is a biotemplated material fabricated by Si melt-infiltration of carbon preforms from wood pyrolysis. In this work, porous bioSiC ceramics from five different wood precursors, with porosities between 45 and 72% were studied for their feasibility in filtering applications. Gas permeability and mechanical stability were investigated as a function of the microstructure of the starting wood precursor. Air-permeation performance at room temperature was measured for a range of flow rates, and the permeability constants were assessed by fitting of Forchheimer's equation to the experimental data. Darcian permeabilities were achieved in the range 10 −11 -10 −12 m 2 , while inertial terms were in the range 10 −7 -10 −8 m, showing a correlation with the average pore size and orientation of the larger channels. Regarding the mechanical stability, maximum compressive strength values were reached in the range of 3-115 MPa. These results improve our understanding of the ways in which the microstructure influences permeability and mechanical robustness, enabling the device requirements to be tailored by selecting the wood precursor. It was also shown that these materials are promising for hot-gas filtering applications.

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“…Moreover, Osteoblasts, chondrocytes and bone marrow mesenchyme stem cells, acquired from patient's soft and hard tissue, can be spread after seeding on bone scaffolds. Besides, the scaffolds will degrade slowly as the bone tissue grows in vivo or in vitro [18][19][20]. The traditional fabrication of the scaffolds depends on some conventional techniques, such as foam replication, melt molding, solvent casting, etc.…”

Section: Introductionmentioning

confidence: 99%

Calcium sulfate bone scaffolds with controllable porous structure by selective laser sintering

et al. 2015

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The calcium sulfate (CaSO 4 ) bone scaffolds with high porosity and interconnectivity and controllable pore size were prepared by using selective laser sintering. The phase composition, micro morphology and biocompatibility were investigated by using X-ray diffraction, scanning electron microscopy and microculture tetrazolium test. The results showed that the CaSO 4 powders fused better and a more compact structure was built due to the decrease of holes in the scaffold at laser power of 7 W compared with 6 W or lower. At this time, both compressive strength and fracture toughness were optimal. While CaSO 4 decomposed and resulted in the mechanical properties decreasing when laser power further increased. Consequently, the mechanical properties of the scaffolds decreased. Moreover, the osteoblast-like cells attached on the scaffolds were obtained by cell culture in vitro. The results revealed that the cells could adhere and grow well on the scaffolds.

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Permeability of porous gelcast scaffolds for bone tissue engineering

Cited by 67 publications

References 46 publications

Ovalbumin as foaming agent for Ti6Al4V foams produced by gelcasting

Ovalbumin as foaming agent for Ti6Al4V foams produced by gelcasting

Permeability and mechanical integrity of porous biomorphic SiC ceramics for application as hot-gas filters

Calcium sulfate bone scaffolds with controllable porous structure by selective laser sintering

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