Peroneal intraneural ganglion cyst with a nearly invisible joint connection (even to advocates of the articular theory): illustrative case

Abstract

BACKGROUND The articular (synovial) theory describes the formation of intraneural ganglion cysts through defects in the capsule of synovial joints. While the articular theory is gaining significant traction in the literature, it is not universally accepted. Therefore, the authors present a case of a plainly visible peroneal intraneural cyst, although the subtle joint connection was not identified specifically at the time of surgery, with subsequent rapid extraneural cyst recurrence. The joint connection was not immediately evident on review of the magnetic resonance imaging, even to the authors who have a large experience with this clinical entity. The authors report this case to demonstrate that all intraneural ganglion cysts have joint connections, although they may be difficult to identify. OBSERVATIONS An occult joint connection in the intraneural ganglion poses a unique diagnostic and management dilemma. High-resolution imaging is a valuable tool used to identify the articular branch joint connection as part of the surgical planning. LESSONS Based on the articular theory, all intraneural ganglion cysts will have a joint connection through an articular branch, although this may be small or nearly invisible. Failure to appreciate this connection can lead to cyst recurrence. A high index of suspicion of the articular branch is needed for surgical planning.

Differential Diagnosis of “Foot Drop”: Implications for Peripheral Nerve Surgery

“…Common mechanisms of peroneal nerve injury include traction secondary to knee dislocation with multi-ligament injury, 30,31 entrapment beneath tight anatomical structures, 32 and compression from a space-occupying mass such as a ganglion cyst. 33 Approximately 31% of patients with a multi-ligament injury involving the posterolateral corner will also have a concomitant peroneal nerve palsy from traction/rupture. 31 Amongst entrapment neuropathies, the peroneal nerve is the most common for the lower extremity.…”