Peroxidation in muscle and liver tissues from fish in a contaminated river due to a petroleum refinery industry

Avcı, Aslıhan; Kaçmaz, Murat; Durak, İlker

doi:10.1016/j.ecoenv.2003.10.003

Cited by 140 publications

(47 citation statements)

References 31 publications

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“…This may be a defence mechanism against liposoluble contaminants, although lipid accumulation was regarded as a normal physiological storage (Sylvie et al, 1996). According to some authors, the intensity of vacuolation and necrosis were strongly associated with changes in the liver enzyme activity, which regulated the oxidative stress mechanism and the metabolic rate (Manna et al, 2004;Avci et al, 2005). A previous study also showed histopathological lesions in the liver after treatment with cypermethrin or benalaxyl in lizards (Chen et al, 2016;Wang et al, 2014).…”

Section: Histopathologymentioning

confidence: 95%

Tissue distribution, metabolism and hepatic tissue injury in Chinese lizards (Eremias argus) after a single oral administration of lambda-cyhalothrin

Chang

Wang

et al. 2016

Environmental Pollution

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a b s t r a c tLambda-cyhalothrin (LCT) is a widely used pyrethroid with neurotoxicity. However, little is known about the toxicokinetics of LCT in reptiles. In this study, the absorption, distribution, metabolism and excretion of LCT in Chinese lizards (Eremias Argus) were determined following a single dose (10 mg kg À1 ) treatment. In the liver, brain, gonads and skin, LCT levels peaked within several hours and then decreased rapidly. However, the concentration of LCT gradually increased in the fat tissue. More than 90% of the LCT dose was excreted in the faeces. One LCT metabolite, 3-phenoxybenzoic acid (PBA), was detected in lizard plasma and tissues. PBA preferentially accumulates in the brain and plasma. The half-life of PBA in the brain was 3.2 days, which was 35.4-fold greater than that of LCT. In the plasma, the concentration of PBA was significantly higher than that of LCT. The bioaccumulation of LCT in tissues was enantioselective, and the enantiomeric fractions (EF) ranged from 0.72 to 0.26. The preferential accumulation of enantiomers changed according to exposure time, but the reasons behind this phenomenon were not clear. For pathological analysis, vacuolation of the cytoplasm and large areas of necrosis were observed in the liver sections after 168 h of dosing. The liver tissues exhibited both decreases in the hepatosomatic index and histopathological lesions during the exposure period. In this study, the effect concentration of LCT in lizards was 200-fold lower than its LD 50 value used in risk assessments for birds. These results may provide additional information for the risk assessment of LCT for reptiles and indicate that birds may not be an ideal surrogate for reptile toxicity evaluation.

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Section: Histopathologymentioning

confidence: 95%

Tissue distribution, metabolism and hepatic tissue injury in Chinese lizards (Eremias argus) after a single oral administration of lambda-cyhalothrin

Chang

Wang

et al. 2016

Environmental Pollution

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“…In previous studies the liver was found to be stronger to face of oxidative stress than the other tissues and a uniform organ with the highest antioxidative enzyme activities (SOD, CAT). This could be related to the fact that the liver is the site of multiple oxidative reaction and maximal free radical generation (Gul et al, 2004;Avci et al, 2005).…”

Section: Resultsmentioning

confidence: 99%

Sodium Fluoride Toxicity on Blood Parameter and Catalase Activity of Indian Fresh Water Iarvicidal fish Channa straitus

Chauhan¹,

Singh²,

Singh³

2014

Curr World Environ

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Due to its high reactivity fluoride does not occur in the element state in nature. WHO and ISO 10500 recommend that the fluoride content in drinking water should be in the range of 1.0-1.5 ppm. Fluoride ions are directly toxic to aquatic life and accumulated in the tissues where absorption rates exceed excretion rates. Duration of exposure also affects toxicity. Snake headed fish (Channa straitus) is larvivorous and edible fish species of India and South East Asia. After exposure of NaF (60ppm) it has been observed that body weight and organosomatic index has been decreased significantly. Some leucocytes also decreased i.e. Neutrophils 1.125-2.68%, Monocytes 0.66%-35.66%. But Lymphocytes 2.9-10.01% and eosinophils 7.6-20.88% increased. Hb% also decreased. After estimation of Catalase activity it has been observed its activity is increased in liver may be associated with increased oxidative stress. Catalase activity is decreased in brain 0.03% -9.23%.

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“…Catalase production levels in the liver of the fish exposed in treatment C1 and C3 were significantly higher than control at day 14. Liver is the site of multiple oxidative reactions and maximal free radical generation (Avci et al, 2005). This is probably why there was increase in the catalase production levels to act in opposition to the effects of oxidative stress due to the presence of the pollutant.…”

Section: Discussionmentioning

confidence: 99%

Effects of Lead Nitrate on catalase production levels in post juvenile Clarias gariepinus (Burchell, 1822)

Loveline¹,

Samuel²,

Arimoro³

et al. 2018

Int. J. Fish. Aquac.

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The effects of Lead Nitrate on catalase (CAT) production levels in post juvenile Clarias gariepinus were investigated. A total of 250 samples of the fish were acclimatized for two week. Six samples of the fish were exposed to the sub-lethal concentrations of 00, 28, 43 and 57 mg/L with replicate in each case for 28 days. Two samples of the fish were randomly selected from the treatments and control for the bioassay of catalase on the 14 th and 28 th day respectively. The fish organs (kidney, liver and gill) were excised from the fish and homogenized in sodium phosphate buffer (0.2 M, pH 8.0). The data generated were subjected to one-way analysis of variance followed by Duncan Multiple Range test where significant. The results showed that 96 h LC 50 of C. gariepinus exposed to lethal concentrations of Lead Nitrate was 284.189 mg/L. The CAT production levels were significantly higher in the kidney of the fish exposed in 28 mg/L on day 14; 43 and 57 mg/L on day 28, respectively. The CAT production levels were significantly higher in the gill of the fish exposed in 57 mg/L on day 14; 43 and 57 mg/L on day 28 respectively. The CAT production levels were significantly higher in the liver of the fish exposed in 28 and 57 mg/L on day 14 respectively. The highest production mean values of 149.55±43.65 and 152.80±40.40 U/mgprotein were obtained in the kidney of the fish exposed in 57 and 43 mg/L, respectively. Therefore, the kidney of the fish exhibited a better control of the toxicant and as such, catalase production level in this organ should be used in assessing the level of physiological changes in the fish.

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Peroxidation in muscle and liver tissues from fish in a contaminated river due to a petroleum refinery industry

Cited by 140 publications

References 31 publications

Tissue distribution, metabolism and hepatic tissue injury in Chinese lizards (Eremias argus) after a single oral administration of lambda-cyhalothrin

Tissue distribution, metabolism and hepatic tissue injury in Chinese lizards (Eremias argus) after a single oral administration of lambda-cyhalothrin

Sodium Fluoride Toxicity on Blood Parameter and Catalase Activity of Indian Fresh Water Iarvicidal fish Channa straitus

Effects of Lead Nitrate on catalase production levels in post juvenile Clarias gariepinus (Burchell, 1822)

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