Peroxidation Potential and Antioxidant Activity of Serum in Patients with Diabetes Mellitus and Myocard Infarction

Özdemirler, Gül; Mehmetçik, Güldal; Öztezcan, Serdar; Toker, Gülçin; Sıvas, Ahmet; Uysal, M.

doi:10.1055/s-2007-979938

Cited by 52 publications

(25 citation statements)

References 5 publications

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“…For the evaluation of lipid peroxidation (PP) susceptibility, samples were incubated with a cupric sulfate solution (2 mM) at 37°C for 24 h. The PP was calculated by subtracting the MDA concentration obtained at time 0 from that obtained at 24 h [28].…”

Section: Biochemical Methodsmentioning

confidence: 99%

C-Phycocyanin ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells

Pentón‐Rol

Martı́nez-Sánchez

Cervantes‐Llanos

et al. 2011

International Immunopharmacology

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Section: Biochemical Methodsmentioning

confidence: 99%

C-Phycocyanin ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells

Pentón‐Rol

Martı́nez-Sánchez

Cervantes‐Llanos

et al. 2011

International Immunopharmacology

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“…In order to determine susceptibility to lipid peroxidation, serum samples were incubated with a solution of 2 mM copper sulphate at 37 ºC for 24 h. Peroxidation potential was calculated sustracting the relative content of MDA at 24h to the one calculated without copper-induced lipid peroxidation [12].…”

Section: Susceptibility To Lipid Peroxidation Assaymentioning

confidence: 99%

Protective Effects of Mangifera indica L. Extract Against Lipofundininduced Oxidative Stress in Rats

Roche¹

2012

TOPHARMCJ

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Lipofundin is a lipid rich emulsion used in parenteral nutrition. It is known that Lipofundin induces an oxidative stress state characterized by an increase of lipid peroxidation and a dramatic depletion of antioxidants. The aim of the present study was to evaluate the effects of an aqueous extract of Mangifera indica L., on Lipofundin-induced oxidative stress. Male Sprague Dawley rats were treated orally with 200 mg/kg of Vimang®, followed by an intravenous dose of 2 mL/kg Lipofundin, daily, for 8 days. Selected oxidative stress biomarkers were then measured spectrophotometrically. The results showed that Vimang® produced significant (p<0.05) reduction of malondialdehyde, total hydroperoxides and advanced oxidation protein products, while the activities of superoxide dismutase and catalase were positively modulated. A significant (p<0.05) reduction of peroxidation potential and a preservation of glutathione and total antioxidant status was also observed. Our data demonstrated that Vimang® protects against Lipofundin-induced oxidative stress, which is an important finding that further reinforces the antioxidant properties of this natural product.

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“…Several investigators have found an increase in serum lipid peroxide leves, antibody titer against oxidized LDL (oxLDL-Ab), and the susceptibility of LDL or very low-density lipoproteins (VLDL+LDL) to lipid peroxidation in patients with some atherosclerotic risk factors, such as hypercholesterolemia [7,8], diabetes mellitus [9,10], essential hypertension [11,12], aging [13], and those with atherosclerosis [5,6,9,[14][15][16][17]. On the other hand, some restricted experimental [18,19] and clinical evidence [20][21][22][23][24] has suggested that pro-oxidant-antioxidant balance was also affected in obesity.…”

Section: Introductionmentioning

confidence: 99%

An increase in lipoprotein oxidation and endogenous lipid peroxides in serum of obese women

Mutlu-Türkoglu¹,

Öztezcan²,

Telci³

et al. 2003

Clinical and Experimental Medicine

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Endogenous malondialdehyde and diene conjugate levels, the susceptibility of apolipoprotein B-containing lipoproteins to copper-induced lipid peroxidation, and antibody titer against oxidized low-density lipoproteins were increased, but serum antioxidant activity was unchanged in obese women. Serum cholesterol, low-density lipoproteincholesterol, and trigliceride levels were also elevated, but high-density lipoprotein-cholesterol levels remained unchanged in obese women. In vitro, oxidation of apolipoprotein B-containing lipoproteins and levels of antibody against oxidized low-density lipoprotein correlated with body mass index, serum total cholesterol, and low-density lipoproteincholesterol levels in obese women. These results indicate that obesity is associated with increases in endogenous lipid peroxides, oxidation of low-density lipoproteins, and lipids in serum.

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Peroxidation Potential and Antioxidant Activity of Serum in Patients with Diabetes Mellitus and Myocard Infarction

Cited by 52 publications

References 5 publications

C-Phycocyanin ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells

C-Phycocyanin ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells

Protective Effects of Mangifera indica L. Extract Against Lipofundininduced Oxidative Stress in Rats

An increase in lipoprotein oxidation and endogenous lipid peroxides in serum of obese women

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