For automorphic L-functions L(s, π) and L(s, π ) attached to automorphic irreducible cuspidal representations π and π of GLm(QA) and GL m (QA), we prove the Selberg orthogonality unconditionally for m ≤ 4 and m ≤ 4, and under hypothesis H of Rudnik and Sarnak if m > 4 or m > 4, without the additional requirement that at least one of these representations be self-contragradient.