Persimmon (Diospyros kaki L.) leaves: A review on traditional uses, phytochemistry and pharmacological properties

Xie, Chunyan; Xie, Zhihui; Xu, Xin; Yang, Dan

doi:10.1016/j.jep.2015.01.007

Cited by 123 publications

(107 citation statements)

References 34 publications

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“…Natural antioxidants protect and preserve the metabolic activity and cellular viability of cryopreserved bovine spermatozoa [5]. Diospyros kaki is rich in strong antioxidants as represented by high contents of carotenoids [11,33], flavonoids and polyphenols [34][35][36], organic acids and vitamins [11,37], carbohydrates [11,38] and minerals [39]. Olayemi et al [40] and Aljady et al [41] recorded that phenolic acids and flavonoids have strong antioxidant capacity and improved semen quality of preserved semen.…”

Section: Discussionmentioning

confidence: 99%

Effect of Diospyros kaki enriched extender on cattle bull sperm parameters and conception rate

El-Sheshtawy

El-Nattat

2017

APJR

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Section: Discussionmentioning

confidence: 99%

Effect of Diospyros kaki enriched extender on cattle bull sperm parameters and conception rate

El-Sheshtawy

El-Nattat

2017

APJR

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“…However, when quercetin was treated in this culture condition, it suppressed the activating phosphorylation in tyrosine 397 and 861 of FAK and serine 473 of Akt1 in a dose-dependent manner. The IC 50 values were approximately 24.3 µmol/L for tyrosine 397, 10.06 µmol/L for tyrosine 861 of FAK, and 10.7 µmol/L for serine 473 of Akt1. Next, when primary dermal fibroblasts were incubated in the activating culture condition for 24 h, we detected the increased expression of α-SMA.…”

Section: Quercetin Suppresses Activation Of Primary Dermal Fibroblastmentioning

confidence: 92%

Quercetin Shows the Pharmacological Activity to Simultaneously Downregulate the Inflammatory and Fibrotic Responses to Tissue Injury in Association with its Ability to Target Multi-Kinases

2018

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Aim: Previous studies have suggested that quercetin is effective for treating diverse chronic disorders including organ fibrosis and airway and cardiovascular disorders. To access the pharmacological background for its broad efficacy, we examined the ability of quercetin to modulate the inflammatory and fibrotic responses associated with organ injury that commonly underlie the pathogenesis of those disorders. Methods: A cutaneous wound model on rabbit ear was used for in vivo study. Quercetin was topically applied to the wounds, and the number of macrophages and myofibroblasts and the size of the hypertrophic scar formed were estimated. An in vitro study examined the ability of quercetin to inhibit cell-signaling pathways that activate RAW264.7 macrophages and primary dermal fibroblasts and the tyrosine kinase activity of discoidin domain receptor 2. Results: Quercetin reduced the population of macrophages and myofibroblasts and the scar formation in cutaneous wound healing. Quercetin suppressed the signaling pathways activating RAW264.7 macrophages and dermal fibroblasts, which is associated with its inhibition of multiple tyrosine kinases to regulate the pathways. This pharmacological activity of quercetin to simultaneously inhibit the inflammatory and fibrotic responses upon tissue damage by targeting multi-kinases could be the action mechanism to support its broad efficacy for various chronic disorders.

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“…Author(s) agree that this article remains permanently open access under the terms of the Creative Commons Attribution License 4.0 International License well as the incidence of stroke and the extension of the lifespan of hypertensive rats (Uchida et al, 1995;Xie et al, 2015). Reports suggest that consumption of the persimmon fruits is good for human health (Lia et al, 2013;Butt et al, 2015).…”

Section: Introductionmentioning

confidence: 94%

Quality characteristics of dried persimmon (Diospyros kaki Thunb) of different fruit sizes

Cho¹,

Song²,

Cho³

et al. 2017

Afr. J. Biotechnol.

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Fruits of persimmon are considered as one of the health promoting foods which has been established as one of the major fruits in Korea. Persimmon is one of the fruits processed mainly by drying. Quality characteristics of dried persimmon prepared with different fruit sizes of cultivar Sanggandungsi were investigated. Smaller sized fruits showed significantly high weight loss as compared to bigger ones due to drying. On the other hand, bigger sized fruits possessed significantly high value for hardness after 35 days of drying. Size of fruit was not found to be vital for soluble solid contents of dried fruits. One of the important bioactive molecules of persimmon fruits (tannin content) is significantly high in bigger sized fruits as compared to smaller ones. Significant differences in various parameters among different sized fruits indicate that, physicochemical characteristics of dried persimmon fruit could be affected by the fruit size.

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Persimmon (Diospyros kaki L.) leaves: A review on traditional uses, phytochemistry and pharmacological properties

Cited by 123 publications

References 34 publications

Effect of Diospyros kaki enriched extender on cattle bull sperm parameters and conception rate

Effect of Diospyros kaki enriched extender on cattle bull sperm parameters and conception rate

Quercetin Shows the Pharmacological Activity to Simultaneously Downregulate the Inflammatory and Fibrotic Responses to Tissue Injury in Association with its Ability to Target Multi-Kinases

Quality characteristics of dried persimmon (Diospyros kaki Thunb) of different fruit sizes

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