Persistence and outcome of auditory hallucinations in adolescence: A longitudinal general population study of 1800 individuals

Loore, Ellen De; Günther, Nicole; Drukker, Marjan; Feron, Frans; Sabbe, Bernard; Deboutte, Dirk; Os, Jim van; Myin-Germeys, Inez

doi:10.1016/j.schres.2011.01.015

Cited by 91 publications

(79 citation statements)

References 36 publications

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“…This compares to a median prevalence of 5% reported by van Os and colleagues in a meta analysis of mainly adult studies of psychotic symptoms, which supports the idea that psychotic symptoms are more prevalent in childhood compared to adulthood. This is also in line with longitudinal research, which has shown a decline in the incidence of psychotic symptoms in young people followed over time (Bartels-Velthuis et al, 2011, De Loore et al, 2011, Dominguez et al, 2011, Mackie et al, 2011.…”

Section: Discussionsupporting

confidence: 89%

“…A total of 19 studies met criteria for inclusion -5 interview studies (Horwood et al, 2008, Kelleher et al, 2008, Kelleher et al, In Press, Polanczyk et al, 2010, Poulton et al, 2000 and 14 self report questionnaire studies (Barragan et al, 2011, De Loore et al, 2011, Dhossche et al, 2002, Kelleher et al, In Press, Kinoshita et al, 2011, Lataster et al, 2006, Scott et al, 2009a, Scott et al, 2009b, Wigman et al, 2011, Yoshizumi et al, 2004, Yung et al, 2009) (see Table 1). …”

Section: Resultsmentioning

confidence: 99%

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Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-analysis of population-based studies

et al. 2012

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Cannon M. Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-analysis of population-based studies. Psychological Medicine. 2012; 9:1-7. AuthorsIan Kelleher, Dearbhla Connor, Mary C. Clarke, Nina Devlin, Michelle Harley, and Mary Cannon This article is available at e-publications@RCSI: http://epubs.rcsi.ie/psychart/1 -Use LicenceAttribution-Non-Commercial-ShareAlike 1.0 You are free:• to copy, distribute, display, and perform the work.• to make derivative works. Under the following conditions:• Attribution -You must give the original author credit.• Non-Commercial -You may not use this work for commercial purposes.• Share Alike -If you alter, transform, or build upon this work, you may distribute the resulting work only under a licence identical to this one.

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Section: Discussionsupporting

confidence: 89%

Section: Resultsmentioning

confidence: 99%

Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-analysis of population-based studies

et al. 2012

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“…At follow-up, on average two years later, the PLE prevalence was 30% and within the prevalence range (15-38%) reported by several large urban adolescent cohort samples using self-report questionnaires De Loore et al, 2011;Dominguez et al, 2011;Kelleher et al, 2011). Only 39% of children who originally reported PLEs continued to do so two years later.…”

Section: Prevalence Of Plessupporting

confidence: 60%

“…Longitudinal studies following adolescents into adulthood distinguish short-lived or transitory PLEs that may be relatively benign from persistent PLEs that impose a greater likelihood of concurrent, and later, psychiatric morbidity and social impairment (Cougnard et al, 2007;Woods et al, 2009;Dominguez et al, 2011). Recent longitudinal work employing adolescent samples indicates that persistent PLE trajectories, compared with non-persistent trajectories, are associated with the highest levels of internalising psychopathology (i.e., symptoms of anxiety, depression, or social withdrawal) at follow-up (Mackie et al, 2010;De Loore et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…Two studies which adjusted for past psychopathology provide contrasting accounts of the predictive validity of PLE persistence. Wigman et al (2011a) examined adolescent and adult patients over two years and found that PLE persistence did not predict changes in internalising problems, whilst De Loore et al (2011) reported that adolescents with persisting hallucination symptoms were twelve times more likely to report internalising problems at two-year follow-up. Lastly, longitudinal population-based studies have focused typically on the relationship between PLEs and internalising problems only.…”

Section: Introductionmentioning

confidence: 99%

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Persisting psychotic-like experiences are associated with both externalising and internalising psychopathology in a longitudinal general population child cohort

Downs

Cullen

Barragán

et al. 2013

Schizophrenia Research

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Downs, J. (2013). Persisting psychotic-like experiences are associated with both externalising and internalising psychopathology in a longitudinal general population child cohort. Schizophrenia Research, 144(1-3), 99-104. https://doi.org/10.1016/j.schres.2012.12.009Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. And where the final published version is provided on the Research Portal, if citing you are again advised to check the publisher's website for any subsequent corrections. General rightsCopyright and moral rights for the publications made accessible in the Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognize and abide by the legal requirements associated with these rights.•Users may download and print one copy of any publication from the Research Portal for the purpose of private study or research.•You may not further distribute the material or use it for any profit-making activity or commercial gain •You may freely distribute the URL identifying the publication in the Research Portal Take down policy If you believe that this document breaches copyright please contact librarypure@kcl.ac.uk providing details, and we will remove access to the work immediately and investigate your claim. Background: Persisting psychotic-like experiences (PLEs) are associated with an increased risk of internalising symptoms in adolescence. Whether this association holds similarly for externalising symptoms, and from mid-childhood, is unclear. This prospective study investigated the extent to which PLE persistence was associated with internalising and externalising psychopathology in a community sample of children aged 9-11 years at study commencement. Methods: 8099 children (mean age 10.4 years) completed questionnaires assessing PLEs, externalising and internalising symptoms. A subsample of 547 children completed reassessment, on average, two years later. Results: Two-thirds (66%) of children reported PLEs at baseline. Approximately two years later, PLEs persisted in 39% of those children. After adjustment for previous psychopathology and other potential confounds, children with persisting PLEs were at higher risk for internalising (odds ratio [OR]=1.94; 95% confidence interval [CI] 1.13-3.34) and externalising (OR=1.97; 95% CI 1.19-3.26) psychopathology than children whose PLEs remitted; and, than children who never presented PLEs. Conclusions: Persistent PLEs from mid-childhood are associated with later internalising and externalising psychopathology in the general population, whereas transitory PLEs may be part of a spectrum of normative childhood development. Interventions that target persistent PLEs may contribute to a reduction in common chi...

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The psychosis spectrum in a young U.S. community sample: findings from the Philadelphia Neurodevelopmental Cohort

et al. 2014

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Little is known about the occurrence and predictors of the psychosis spectrum in large non-clinical community samples of U.S. youths. We aimed to bridge this gap through assessment of psychosis spectrum symptoms in the Philadelphia Neurodevelopmental Cohort, a collaborative investigation of clinical and neurobehavioral phenotypes in a prospectively accrued cohort of youths, funded by the National Institute of Mental Health. Youths (age 11-21; N57,054) and collateral informants (caregiver/legal guardian) were recruited through the Children's Hospital of Philadelphia and administered structured screens of psychosis spectrum symptoms, other major psychopathology domains, and substance use. Youths were also administered a computerized neurocognitive battery assessing five neurobehavioral domains. Predictors of psychosis spectrum status in physically healthy participants (N54,848) were examined using logistic regression. Among medically healthy youths, 3.7% reported threshold psychotic symptoms (delusions and/or hallucinations). An additional 12.3% reported significant subpsychotic positive symptoms, with odd/unusual thoughts and auditory perceptions, followed by reality confusion, being the most discriminating and widely endorsed attenuated symptoms. A minority of youths (2.3%) endorsed subclinical negative/disorganized symptoms in the absence of positive symptoms. Caregivers reported lower symptom levels than their children. Male gender, younger age, and non-European American ethnicity were significant predictors of spectrum status. Youths with spectrum symptoms had reduced accuracy across neurocognitive domains, reduced global functioning, and increased odds of depression, anxiety, behavioral disorders, substance use and suicidal ideation. These findings have public health relevance for prevention and early intervention.

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Persistence and outcome of auditory hallucinations in adolescence: A longitudinal general population study of 1800 individuals

Abstract: Although hallucinations in adolescents are a common and mainly transitory phenomenon, the persistence rate over time is far from negligible, and associated with clinical deterioration.

Cited by 91 publications

References 36 publications

Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-analysis of population-based studies

Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-analysis of population-based studies

Persisting psychotic-like experiences are associated with both externalising and internalising psychopathology in a longitudinal general population child cohort

The psychosis spectrum in a young U.S. community sample: findings from the Philadelphia Neurodevelopmental Cohort

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