Persistence of antibacterial agents in marine sediments

Hektoen, Halvor; Berge, John Arthur; Hormazábal, Víctor; Yndestad, Magne

doi:10.1016/0044-8486(94)00310-k

Cited by 299 publications

(168 citation statements)

References 24 publications

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“…This antibiotic has been known for its weak adsorption and easy leaching in soil. 50,51 Due to the discharge of wastewater from lagoon 2, the receiving stream had been heavily contaminated with various antibiotics (Table 3). The concentrations of most antibiotics in the receiving stream were much higher than those in surface water reported in previous studies.…”

Section: Occurrence In the Receiving Environmentsmentioning

confidence: 99%

Use patterns, excretion masses and contamination profiles of antibiotics in a typical swine farm, south China

Zhou

Ying

Zhang

et al. 2013

Environ. Sci.: Processes Impacts

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The objective of this study was to screen the occurrence of 50 antibiotics in a typical swine farm in southern China, which includes animal feeds, waste collection and treatment systems (lagoons and anaerobic digesters), and receiving environments (vegetable fields, streams, and private wells). Nine antibiotics were found in the feeds for different stages of the development of pigs in the swine farm, at concentrations ranging from 2.37 AE 0.16 ng g À1 (sulfamethazine) to 61 500 AE 11 900 ng g À1 (bacitracin). 11, 17 and 15 target compounds were detected in feces, flush water, and suspended particles in the swine farm, respectively. Based on the survey of feeds and animal waste from the farm, chlortetracycline, tetracycline, bacitracin and florfenicol in the feces, flush water and suspended particles mainly originated from the feeds, while most sulfonamides, including doxycycline, oxytetracycline, fluoroquinolones, macrolides and trimethoprim, were mainly from injection and other oral routes. The daily excretion masses of antibiotics per pig calculated based on animal waste had the following order: sows (48.3 mg per day per pig), piglets (18.9 mg per day per pig), growing pigs (7.01 mg per day per pig) and finishing pigs (1.47 mg per day per pig), indicating that the usage of antibiotics (type and dosage) and excretion masses are related to the growth stage of pigs. Chlortetracycline and bacitracin are the main contributors to the total excretion mass of antibiotics from pigs at different stages of development in the farm. The waste treatment system (lagoons and anaerobic digesters) was found to be ineffective in the elimination of antibiotics. The detection of some antibiotics in the surrounding environments of the farm (the well water, stream water and vegetable field soil) was a reflection of pollution from the swine farm. Environmental impactAntibiotics are commonly used in both human and animal therapy. Particularly in animal therapy the usages span from therapeutic, prophylactic and subtherapeutic. The extensive use of antibiotics in livestock industry has become an increasing concern due to the potential risks posed by their residues to the environment and human health. So far, previous studies on antibiotic residues in animal farms have been limited and most of them are focused on selected groups of antibiotics such as tetracyclines and sulfonamides. This study screened for the rst time the occurrence and fate of 11 classes of antibiotics (in total 50 compounds selected based on their usage in China) in a typical swine farm in China, and evaluated the fate of the detected antibiotics from administration to excretion, and from waste collection and treatment systems (lagoons and anaerobic digesters) to the receiving environments (private wells, streams and vegetable elds). Feeds and animal waste (ush water and fecal samples) from different breeding units of the farm were collected to investigate the usage patterns of antibiotics (type, dosage, administration route) in the swine farm, and to estimate dail...

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Section: Occurrence In the Receiving Environmentsmentioning

confidence: 99%

Use patterns, excretion masses and contamination profiles of antibiotics in a typical swine farm, south China

Zhou

Ying

Zhang

et al. 2013

Environ. Sci.: Processes Impacts

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“…As a general rule drugs administered by oral route are slowly absorbed and excreted with deject (VV, 1981;Alderman and Michel, 1992;Lunestad et al, 1993). As a consequence, animal waste from intensive aquaculture contains antibiotics and other drugs in active forms: it has been demonstrated that 70±80% of drugs administered as medicated feed during a treatment period, ends up into the environment (Hektoen et al, 1995).…”

Section: Introductionmentioning

confidence: 99%

“…It is quite persistent (approximately 150 days half-life, in surface sediment, Hektoen et al, 1995), and has been found in the wastewater of a sea bass intensive aquaculture station, during a treatment period at levels of 50 lg l À1 (Migliore et al, 1995b).…”

Section: Introductionmentioning

confidence: 99%

Phytotoxicity to and uptake of flumequine used in intensive aquaculture on the aquatic weed, Lythrum salicaria L.

2000

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Phytotoxicity of Flumequine on the aquatic weed Lythrum salicaria L. was determined by two laboratory models: a single concentration test, by which the e ects of 100 mg l À1 were evaluated after 10, 20, 30 days and a multiple concentration test, by which the e ects of 5000±1000±500±100±50 lg l À1 were evaluated after 35-day exposure. 100 mg l À1 are highly toxic and signi®cantly decrease the growth of plants; this e ect increases with time. Concentrations between 5000 and 50 lg l À1 induced hormesis in plants, by signi®cantly increasing mean number and dimension of leaves and secondary roots. The e ect is the highest at 50 lg l À1 and decreases with increase in concentration. Both toxic e ect and hormesis can be related to plant drug uptake, quite high, in the order of lg g À1 . The ecological implication of Flumequine contamination in aquatic environments and the possible use of Lythrum salicaria for bioremediation and/ or monitoring technique are discussed. Ó

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“…Several studies have demonstrated the presence of antibacterial residues in fish farms (Weston, 1996;Capone et al, 1996;Herwig et al, 1997). Recent studies have shown that many antibiotics persist in the sediment and in the aquatic environment for several months following administration (Bjorklund et al, 1991;Lai et al, 1995;Pouliquen & Le, 1996;Hirsch et al, 1999;Miranda & Zemelman, 2002).The residues of antibacterial agents may affect the sedimentary microbial community and introduce antibiotic resistance in the bacteria (Hektoen et al, 1995;Tendencia & Dela Pena, 2002). Mc Phearson et al (1991 have observed that individual and multiple antibiotic resistances are associated with antimicrobial use.…”

Section: Aquaculturementioning

confidence: 99%