Persistence of HIV-Associated Neurocognitive Disorders in the Era of Antiretroviral Therapy

King, Jennifer; Jensen, Brigid K.; Gannon, Patrick J.; Akay, Cagla

doi:10.5772/52683

Cited by 2 publications

(2 citation statements)

References 276 publications

(373 reference statements)

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“…Illicit drug use, as well as alcohol abuse, put HIV-positive patients at a greater risk for HAND [6,[218][219][220][221][222][223][224]. The prevalence of HIV infection is 11-17% among illicit drug users, and methamphetamine (METH) is among the most frequently abused drug with well-known toxic effects on the BBB and in the CNS [220].…”

Section: The Impact Of Co-morbidities On Handmentioning

confidence: 99%

Current Perspectives in HIV Infection

Saxena¹

2013

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is a Medical Microbiologist at CSIR-Centre for Cellular and Molecular Biology (CCMB) in India. The main research interests of his group are to understand the epidemiology and molecular mechanisms of host-defense during human viral infections and to develop new predictive, preventive and therapeutic strategies for them using JEV and HIV as a model. His research work has been published in various high impact factor journals with high citation. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award and named as "Global Leader in Science" by The Scientist magazine (USA).

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Section: The Impact Of Co-morbidities On Handmentioning

confidence: 99%

Current Perspectives in HIV Infection

Saxena¹

2013

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“…A healthcare worker in this study is one who offers HIV care and includes; medical officers, clinical officers, nurses and counselors. Guidelines for HIV care entail HIV prevention, counseling and testing, linkage to care and follow-up, treatment, and retention in care and psychosocial support to PLWH and their families [ 14 ]. Although the Ugandan HIV guidelines added routine screening for depression to improve HIV care delivery [ 15 ], little consideration has been given to HAND screening.…”

Section: Introductionmentioning

confidence: 99%

Screening HIV associated neurocognitive disorders using international HIV dementia scale: closing the gap through an educational intervention for healthcare workers

Namagga¹,

Nambozi²,

Rukundo³

et al. 2023

Pan Afr Med J

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Introduction the study assessed the effect of an educational intervention on healthcare workers´ knowledge regarding the use of the International HIV Dementia Scale (IHDS) in screening HIV-associated neurocognitive disorder (HAND) at The AIDS Support Organization (TASO) centres in Uganda. Methods we recruited healthcare workers in southwestern and central Uganda. Data were collected by a questionnaire, cleaned, and analyzed using means and standard deviations. A paired t-test assessed mean knowledge score differences pre-and post-intervention. We used One-Way ANOVA for mean score differences between sites and cadres. Statistical significance was taken at p ≤ 0.05 and 95% confidence interval. Prevalence of HAND for clients screened during educational intervention was computed. Results mean age was 36.38 years (SD = 7.80) and mean years of experience 8.92 (SD = 6.52). A paired t-test showed that pre-intervention mean score (Mean= 20.38, SD 2.94) was statistically different from post-intervention mean score (Mean=22.24, SD 2.15) at t (36) = - 4.933, p > 0.001). One-way ANOVA showed counselors were statistically different from clinical officers´ pre-intervention (Mean difference 4.432 (95% CI: 0.1- 8.85, p= 0.049) and post-intervention (Mean difference 3.364 (95% CI: 0.07 - 6.65, p= 0.042) respectively. There was no difference in mean knowledge scores between sites pre-intervention (F (4, 32) = 0.827, p = 0.518) and post-intervention (F (4, 32) = 1.299, p = 0.291). Of the 500 clients screened, 72.2% were positive for HAND. Conclusion the educational intervention improved healthcare workers´ knowledge regarding screening HAND using IHDS at TASO centres in Southwestern and Central Uganda.

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Persistence of HIV-Associated Neurocognitive Disorders in the Era of Antiretroviral Therapy

Cited by 2 publications

References 276 publications

Current Perspectives in HIV Infection

Current Perspectives in HIV Infection

Screening HIV associated neurocognitive disorders using international HIV dementia scale: closing the gap through an educational intervention for healthcare workers

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