Persistence of metalaxyl residues on tomato fruit using high performance liquid chromatography and QuEChERS methodology

Malhat, Farag

doi:10.1016/j.arabjc.2012.12.002

Cited by 35 publications

(26 citation statements)

References 5 publications

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“…So, results suggested that period 7 days is safe to harvest after applying with recommended dose of metalaxyl on tomato and will be safe for the consumer's health. These results in line with Malhat (2012) who reported that half-life of metalaxyl in tomato was 1.81 days and the initial deposit of metalaxyl in tomato fruit was 2.39 mg/kg and was decreased to 0.105mg/kg after 7 days of treatment. FAO specification (1992).…”

Section: Resultssupporting

confidence: 91%

Thermal Storage Effect on Metalaxyl and Detection of Its Residues on Tomato and Their Relevant Impurities

Ramadan¹

2018

Journal of Applied Plant Protection

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Metalaxyl fungicide under trade name vacomil 35% wettable powder (WP) was applied on tomato at the recommended dosage 262.5 g a.i./ ha to study the residues and dissipation rate of tested fungicide under field condition by LCMS/MS. Also, the tested fungicide was stored according to Food and Agriculture Organization (FAO) for 14 days at 54 ± 2ºC to study the effect of thermal storage on degradation of metalaxyl active ingredient and stability of their relevant impurities (2,6-dimethylaniline) beside its physical properties. Data illustrated that residues of metalaxyl reached below the maximum residue limit (MRL) of metalaxyl after 7 days from application at the recommended dosage. The half-life (t 1/2 ) for metalaxyl degradation was 1.84 days. Metalaxyl active ingredient was slightly affected with thermal storage and become conformity with FAO specifications and half-life (t 1/2 ) for metalaxyl active ingredient was 8.99 days. 2,6-dimethylaniline as relevant impurities of metalaxyl was increased by extending storage time. It became non conformity with FAO specification under thermal storage where, it was 0.024% before one day of storage and after 14 days of storage reached 0.042% recording increasing rate 75%. All physical properties tests passed successfully and became conformity with FAO specifications.

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Section: Resultssupporting

confidence: 91%

Thermal Storage Effect on Metalaxyl and Detection of Its Residues on Tomato and Their Relevant Impurities

Ramadan¹

2018

Journal of Applied Plant Protection

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“…Several sorbents have been reported as d-SPE cleanup sorbents in plant matrices, especially PSA, C18 and GCB. [51][52][53][54][55][56][57] Alternatively, sorbents such as oasis HLB ® , chitosan and fluorinated sorbent (F) have already been used. [58][59][60] Among the commonly used sorbents cited above, PSA is used for removing sugars, fatty acids, organic acids, lipids and some polar pigments, 34,61 while C18 sorbent is used for removing nonpolar compounds, such as lipids and fatty acids, from fatty matrices (lipid content > 2%).…”

Section: Optimization Of the D-spe Clean-up Stepmentioning

confidence: 99%

Determination of Phenolic Compounds in Red Sweet Pepper (Capsicum annuum L.) using a Modified QuEChERS Method and UHPLC-MS/MS Analysis and Its Relation to Antioxidant Activity

Rodrigues

Nicácio

Jardim

et al. 2019

J. Braz. Chem. Soc.

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In the present work, a fast, easy and efficient analytical method was developed and validated for the determination of phenolic compounds (4-hydroxybenzoic, vanillic, caffeic, p-coumaric, sinapic, ferulic and ellagic acids, and naringenin) in red sweet pepper. Extraction of phenolic compounds was carried out using the quick, easy, cheap, effective, rugged and safe (QuEChERS) method, followed by separation and detection using ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). When the acetate version of the QuEChERS method was used, higher amounts of the phenolic compounds were extracted. In the dispersive solid phase extraction (d-SPE) clean-up step, combination of 50 mg of octadecylsilane (C18) and 7.5 mg of graphitized carbon black (GCB), resulted in the greatest removal of interferents, especially carotenoids, without significant retention of phenolic compounds. The recoveries for the proposed method were 82-103%, the limits of quantification were 2-150 μg kg-1 , and the precision values expressed in terms of relative standard deviation (RSD) were ≤ 15%. The method developed was successfully applied to the analysis of different red sweet pepper cultivars.

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“…Diff erent species, weather conditions, the physical and chemical properties of pesticides, method and rate of application may be responsible for the diff erent dissipation rates of this compound (Romeh and Mekky, 2009;Malhat et al, 2012bMalhat et al, , 2014c. In the fi eld, besides the eff ect of some physical and chemical factors such as light, heat, pH and moisture (Agnihothrudu and Muraleedharan, 1990;Chen et al, 1987;Cosby et al, 1972;Miller and Donaldson, 1994;Malhat, 2012) on the degradation of pesticides, growth dilution factor might play a signifi cant role in the degradation of methomyl residues (Agnihothrudu and Muraleedharan, 1990; Bisen and Ghosh Hajara, 2000;Chen and Wan, 1988;Khay et al, 2008;Cabras et al, 1990, Malhat, 2013. Figure 2 shows the decline curve of methomyl in soil.…”

Section: Dissipation Behaviour In Tomatomentioning

confidence: 99%

Degradation profile and safety evaluation of methomyl residues in tomato and soil

Malhat

Watanabe

Youssef

2015

Hellenic Plant Protection Journal

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Summary A high performance liquid chromatography with the photodiode array detector (HPLCDAD) analytical method was developed to determine the residue levels and investigate the dissipation pattern and safety use of methomyl in tomato and soil. Methomyl residues were extracted from tomato and soil samples with ethyl acetate. The extract was cleaned up with the QuEChERS method. The results showed that the average recoveries were in the range of 87.1-94.5%, with RSD of 6.9-11.2%. Limits of detection (LOD) and quantification (LOQ) were 0.005 and 0.007 mg/kg, respectively. The residue levels of methomyl were best described to first order rate kinetics and half-lives ranged from 1.34 to 1.8 days in tomato and soil, respectively. The theoretical maximum residue contributions for methomyl on tomato were found to be less than the maximum permissible intake values even on zero days, therefore consumer health risks are minimal at the recommended dose on tomato.

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Persistence of metalaxyl residues on tomato fruit using high performance liquid chromatography and QuEChERS methodology

Cited by 35 publications

References 5 publications

Thermal Storage Effect on Metalaxyl and Detection of Its Residues on Tomato and Their Relevant Impurities

Thermal Storage Effect on Metalaxyl and Detection of Its Residues on Tomato and Their Relevant Impurities

Determination of Phenolic Compounds in Red Sweet Pepper (Capsicum annuum L.) using a Modified QuEChERS Method and UHPLC-MS/MS Analysis and Its Relation to Antioxidant Activity

Degradation profile and safety evaluation of methomyl residues in tomato and soil

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