2020
DOI: 10.1186/s10194-020-01123-4
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Persistence of pregabalin treatment in Taiwan: a nation-wide population-based study

Abstract: Background: Pregabalin is approved for the treatment of neuropathic pain, fibromyalgia, and seizure disorders, although the pivotal trials were mostly carried out in Europe or North America. The prescribing patterns among different indications in Asia have rarely been explored. Methods: This was a population-based retrospective cohort study based on the National Health Insurance Research Database in Taiwan. Prescriptions of pregabalin were identified, and data regarding demographics, indications, coexisting di… Show more

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Cited by 6 publications
(2 citation statements)
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References 36 publications
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“…In this case, the therapeutic effect of the lower dose may be insufficient, although dose escalation might be precluded by side effects. In addition, ethnic factors could also play a role (42). Although gabapentin and pregabalin have a similar mechanism of action, the two drugs are often used interchangeably in clinical treatment, but the results of the study show that gabapentin has no significant effect compared with placebo.…”
Section: Summary Of Evidencementioning
confidence: 98%
“…In this case, the therapeutic effect of the lower dose may be insufficient, although dose escalation might be precluded by side effects. In addition, ethnic factors could also play a role (42). Although gabapentin and pregabalin have a similar mechanism of action, the two drugs are often used interchangeably in clinical treatment, but the results of the study show that gabapentin has no significant effect compared with placebo.…”
Section: Summary Of Evidencementioning
confidence: 98%
“…In this case, the therapeutic effect of the lower dose may be insufficient, although dose escalation might be precluded by side effects. In addition, ethnic factors could also play a role (42). Although gabapentin and pregabalin have a similar mechanism of action, the two drugs are often used interchangeably in clinical treatment, but the results of the study show that gabapentin has no significant effect compared with placebo.…”
Section: Summary Of Evidencementioning
confidence: 98%