Persistent alanine aminotransferase elevation among the general Iranian population: Prevalence and causes

Abstract

NAFLD is the most common cause of persistently elevated serum ALT level among the general population of Iran.

Non-alcoholic Fatty Liver Disease: East Versus West

“…48,49 This is in sharp contrast to Asian studies where the mean BMI is about 29 Kg/m 2 in India 53,54 ; 24 in Korea, 17 27 in Sri Lanka, 55 23 in China, 52 and 23 in Japan. 19 Initial studies from India that used the international criteria 56 for defining overweight and obesity found obesity in only 12-30% of patients 57,58 compared with 30-100% in Western studies depending on the population studied.…”

“…Thus, NAFLD probably accounted for about 60-65% of all patients with raised transaminases in Iran. 27 In Taiwan, 34% of all patients with raised transaminases are due to NAFLD, with the figures increasing to 60% in patients without alcohol or viral hepatitis. 28 Non-alcoholic fatty liver disease accounts for relatively lower proportion of patients with raised transaminases in India and Taiwan as hepatitis B and C together account for about 40% of cases in these populations.…”

Prevalence of Nonalcoholic Fatty Liver Disease and Economy

“…To be specific, the three surveys in Iran presented a significant difference. The survey conducted by Jamali et al [23] recruited 2,292 subjects from the cities and villages in Golestan Province. The studies by Eshraghian et al [24] and Lankarani et al [25] were conducted in Kavar and Shiraz, Fars Province.…”

Predictive Factors of Steatosis and Non-Alcoholic Steatohepatitis in Morbidly Obese Patients Undergoing Bariatric Surgery

“…NASH prevalence in normal population is 10% to 20% and in people with severe obesity is almost 37% (15).…”