“…Etiology of the PGAD -Psychological factors such as sex-related emotional problems, anxiety disorder, depressive disorder, and sex-abuse [3], Physiological factors -central mechanisms such as central dopaminergic dysfunction and hormonal [2,3], Pelvic vascular malformation [3], Mechanical -overactive pelvic floor muscles [1], Dietary -phytoestrogens like soy, phyto-estrogens are phytochemicals present in plants are known for their anticancer, antioxidant, immunitypotentiating, neuropharma-cological and detoxifying functions [1,3,4], Medications -such as serotonin [1,3]. Pathogenisis -The neuropathogenisis of PGAD hypothized as stress, drugs, substances, polyneuropathy, menopause, pelvic vascular anomaly, and mechanical irritations affect pudendal nerve and dorsal clistoral nerve, and the product of this will be PGAD along with the RLS/RGS and overactive bladder [1,3]. Stress, drugs, substances, polyneuropathy, menopause, pelvic vascular anomaly, and mechanical irritations affect pudendal nerve and dorsal clistoral nerve, and the product of this will be PGAD along with the RLS/RGS and overactive bladder [1,3].…”