“…8 The basement membrane, located between the mucosal layer and the lamina propria, contains type IV collagen as its main component, and contains a protein that adheres the basal cells of the epidermal layer to the lamina propria because it has a dense plate. 9,10 The superficial layer of the lamina propria is a loose tissue that is easily damaged, and the Reinke's space is a potential space between the vocal mucosa and the vocal ligaments, mainly composed of the submucosal tissue and the superficial layer of the lamina propria. The loose connective tissue in this area is an important tissue essential for vocal cord vibration, but edema easily occurs due to poor lymphatic drainage.…”