Persistent Hypercalcemia Leading to Acute Pancreatitis in a Patient with Relapsed Myeloma and Renal Failure

Çeli̇k, İsmai̇l; Apraş, Ş; Kars, Ayse; Barışta, İbrahim; Güllü, İbrahi̇m; Güler, Nilüfer; Kansu, Emin

doi:10.1159/000045004

Cited by 4 publications

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There are several case reports of pancreatitis secondary to hypercalcaemia of malignancy in the literature. These are frequently of neuroendocrine tumours [16,17], haematological malignancies [18][19][20][21][22][23] or solid cancers with bone metastasis [24][25][26][27][28]. There is a single documented case of acute pancreatitis secondary to hypercalcaemia related to cancer of unknown primary, however this was a neuroendocrine tumour, with bone metastases present [29].…”

Section: Malignancymentioning

confidence: 99%

The Management of Resistant Hypercalcaemia Secondary to Cancer of Unknown Primary and Presenting with Pancreatitis

George

Reed

Patel

et al. 2019

Reports

View full text Add to dashboard Cite

We present a 31-year-old female who presented to the general surgical take with epigastric pain associated with a raised amylase and corrected calcium on admission. Computed tomography confirmed acute pancreatitis and also demonstrated a 15 cm liver tumour. She was subsequently diagnosed with cancer of unknown primary with liver metastases. The patient’s pancreatitis symptoms improved with conservative management, but her calcium proved quite resistant to basic measures. Further input was sought from the medical on-call endocrinology and oncology teams to help manage this patient’s hypercalcaemia, which included pamidronate, zolendronate, and denusomab, but ultimately it only improved significantly following chemotherapy. This case to our knowledge is the only one of its kind and highlights the importance of early multidisciplinary team involvement across specialties to help manage complex patients.

show abstract

Section: Malignancymentioning

confidence: 99%

The Management of Resistant Hypercalcaemia Secondary to Cancer of Unknown Primary and Presenting with Pancreatitis

George

Reed

Patel

et al. 2019

Reports

View full text Add to dashboard Cite

show abstract

“…Wahrscheinlich ist die Hyperkalzämie per se und nicht der primäre Hyperparathyreodismus der Trigger für eine akute Pankreatitis, da auch Hyperkalzämien durch andere Ursachen (Malignome) zu einer Pankreatitis führen können [45,46]. Pathogenetisch werden entweder Kalziumablagerungen in den Azini mit nachfolgender Entzün-dung oder eine hyperkalzämiegetriggerte Aktivierung von Trypsinogen diskutiert [47,48].…”

Section: E Die Korrektur Des Hypoparathyreodismus Durch Vitamin-d-gabunclassified

Endokrine Störungen und Verdauungstrakt

Wellhöner

2011

Gastroenterologe

View full text Add to dashboard Cite

In der Interaktion der Organsysteme zum Erhalt der Körperhomöostase besitzen endokrinologische Regelsysteme eine übergeordnete und integrative Rolle. In diesem System ist die Interaktion der hormonellen Steuerung mit anderen Organsystemen sehr komplex. Viele eher unspezifische klinische Beschwerden können Ausdruck einer zugrunde liegenden Erkrankung des Endokrinums sein. Dieser Artikel fokussiert zum einen auf die gastrointestinalen Symptome primär endokriner Erkrankungen und möchte zum anderen Zusammenhän-ge zwischen endokrinologischen und gastroenterologischen Erkrankungen aufzeigen. Von besonderem Interesse sind hierbei Erkrankungen der Schilddrüse, der Nebenschilddrüse und endokrine Tumoren des Pankreas.

show abstract

Acute pancreatitis due to hypercalcemia related to bone metastasis from breast cancer

Chen

Huang

Hsieh

et al. 2011

QJM

View full text Add to dashboard Cite

Persistent Hypercalcemia Leading to Acute Pancreatitis in a Patient with Relapsed Myeloma and Renal Failure

Cited by 4 publications

References 6 publications

The Management of Resistant Hypercalcaemia Secondary to Cancer of Unknown Primary and Presenting with Pancreatitis

The Management of Resistant Hypercalcaemia Secondary to Cancer of Unknown Primary and Presenting with Pancreatitis

Endokrine Störungen und Verdauungstrakt

Acute pancreatitis due to hypercalcemia related to bone metastasis from breast cancer

Contact Info

Product

Resources

About