Persistent measles virus infection of the intestine: confirmation by immunogold electron microscopy.

Abstract

This study sought to investigate persistent measles virus infection of the intestine: a novel protocol for immunogold electron microscopy was developed using a polyclonal anti-measles nucleoprotein antibody on reprocessed, formalin fixed paraffin wax embedded tissue sections.

The genetics of inflammatory bowel disease: diagnostic and therapeutic implications

“…[44] Moreover, persistent measles infection has been detected in the intestinal tissue of 5 patients with CD by immunogold electron microscopy. [45] Epidemiological studies from Sweden would also suggest that there is an increased incidence of CD but not UC in people born during periods of documented measles epidemics. [46] These studies have raised the possibility that the neonate is more susceptible to either acute or persistent measles infection on account of its immature immune system.…”

Measles-Mumps-Rubella Vaccine and the Development of Autism or Inflammatory Bowel Disease: The Controversy Should End

“…Although the list of studies is not inclusive, some investigators have shown an association, [39][40][41][42][43][44][45] while others reported no link between the measles vaccination and the development of inflammatory bowel disease. [46][47][48][49][50][51][52] It is important to note that 4 of the seven studies cited above as supporting an association have emanated from the Wakefield group.…”

“…[46][47][48][49][50][51][52] It is important to note that 4 of the seven studies cited above as supporting an association have emanated from the Wakefield group. 39,41,42,44 At this time, epidemiological and pathological studies by different investigators have provided conflicting results. For this reason, many organization have concluded that a link cannot be established.…”

La composante génétique des maladies inflammatoires du tube digestif

“…Plus réce-ment, l'hypothèse d'une infection par le virus de la rougeole dans la maladie de Crohn a été avancée. Deux observations sont en accord avec cette hypothèse : la présence du virus morbilleux dans les lésions intestinales [8] et l'augmentation du risque de développer une maladie de Crohn chez les sujets vaccinés contre la rougeole [9]. Enfin, le rôle d'antigènes intraluminaux non spécifiques de la flore résidente de l'intestin a été évoqué devant l'influence du flux fécal dans le déclenchement des poussées de la maladie.…”