2018
DOI: 10.1177/0194599818778276
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Persistent Postoperative Opioid Use in Older Head and Neck Cancer Patients

Abstract: Objectives Despite the epidemic of opioid overuse among American patients, there are limited data regarding the prevalence of such use among patients with head and neck cancer (HNC). Here, we report on the prevalence of persistent postoperative opioid (PPO) use and its risk factors among older patients with HNC undergoing surgery. Study Design Retrospective cohort study. Setting Surveillance, Epidemiology, and End Results (SEER)-Medicare linked cancer registry-claims database. Subjects and Methods We identifie… Show more

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Cited by 46 publications
(71 citation statements)
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“…Rates of persistent opioid use after curative cancer treatment have been estimated to be between 10.4 to 33.3%, although definitions of persistent use vary between studies. 24,35,36 An additional study showed that cancer survivors had increased rates of chronic opioid use when compared to non-cancer controls, though by 6 years after diagnosis the rates did not differ. 37 Optimally managing cancer patients with opioids requires effective risk stratification methods to identify individuals at higher risk of poor outcomes.…”
Section: Discussionmentioning
confidence: 99%
“…Rates of persistent opioid use after curative cancer treatment have been estimated to be between 10.4 to 33.3%, although definitions of persistent use vary between studies. 24,35,36 An additional study showed that cancer survivors had increased rates of chronic opioid use when compared to non-cancer controls, though by 6 years after diagnosis the rates did not differ. 37 Optimally managing cancer patients with opioids requires effective risk stratification methods to identify individuals at higher risk of poor outcomes.…”
Section: Discussionmentioning
confidence: 99%
“…9 This number is expected to grow 30% over the next 10 years. 21,22 Cancer February 15, 2020 The purpose of this study was to determine the extent, historical trends, and predictors of new-onset persistent opioid use during the first year after the completion of active breast cancer treatment among older adult women. [13][14][15][16][17][18][19] With nearly two-thirds of people with cancer surviving at least 10 years beyond their diagnosis, 20 it is crucial that we understand the burden of high-risk opioid use among cancer survivors resulting from their disease and its treatment.…”
Section: Introductionmentioning
confidence: 99%
“…Newonset persistent opioid use specifically is being increasingly recognized as a serious and common health care complication demanding concerted prevention strategies, including strategies for patients undergoing curative cancer treatment. 21,22 Cancer February 15, 2020 The purpose of this study was to determine the extent, historical trends, and predictors of new-onset persistent opioid use during the first year after the completion of active breast cancer treatment among older adult women. Older adult breast cancer survivors represent one of the largest subsets of the cancer survivor population.…”
Section: Introductionmentioning
confidence: 99%
“…In a retrospective study involving over 390,000 outpatients over the age of 66 years who had undergone minor ambulatory surgery procedures, Alam and colleagues [32] reported that opioid-naive patients >66 years receiving an opioid analgesic medication within 7 days after undergoing a minor surgical procedure were 44% more likely to continue using opioids one year after the operation. In patients >66 yeas undergoing surgery for head and neck cancer, 33% developed persistent opioid use lasting >90 days [33]. Not surprisingly, the incidence was higher in previous opioid users (48% vs. 18.5% in opioid-naive patients).…”
mentioning
confidence: 94%
“…The growing importance of opioid dependency after surgical procedures has been emphasized in recent articles by Goesling et al [29] and others [30][31][32][33][34]. These investigators reported that prescription opioid analgesic use often continued after joint replacement surgery despite the fact that the patients were no longer experiencing pain in the operated joint.…”
mentioning
confidence: 99%