Persistent primary thunderclap headache responsive to gabapentin

Garza, Ivan; Black, David F.

doi:10.1007/s10194-006-0346-7

Cited by 9 publications

(4 citation statements)

References 8 publications

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“…Gabapentin is also indicated for the management of post herpetic neuralgia in adults. Benefit has been reported in gabapentin treatment for hypobaric hypoxia-induced headache, high altitude headache, nummular headache, SUNCT syndrome, chronic cluster headache, post-dural puncture headache, and primary thunderclap headache just to mention headaches disorders [ 18 – 26 ].…”

Section: Discussionmentioning

confidence: 99%

Is gabapentin an effective treatment choice for hemicrania continua?

Spears

2009

J Headache Pain

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The objective of this study is to examine the efficacy of gabapentin for the treatment of hemicrania continua (HC) in cases where patients had difficulty tolerating indomethacin due to adverse effects. A retrospective chart review of nine patients with HC between October 2006 and February 2008. Inclusion criteria included men and women age 18 or above presenting to the headache center with a headache that meets International Headache Society criteria for HC including a response to indomethacin, but were not able to continue on indomethacin secondary to adverse effects. Four patients report being pain free, three patients report a 50–80% reduction of pain, one patient reports a 10% reduction of pain, and one patient reports no change in pain. Seven out of nine patients demonstrated at least a 50% reduction of pain on gabapentin, four patients becoming completely pain free.

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Section: Discussionmentioning

confidence: 99%

Is gabapentin an effective treatment choice for hemicrania continua?

Spears

2009

J Headache Pain

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“…In a case of thunderclap headache because of reversible vasoconstriction syndrome, intravenous nimodipine was helpful [116]. Another case reported efficacy of gabapentin [117].…”

Section: Primary Thunderclap Headache (46)mentioning

confidence: 99%

Treatment of miscellaneous idiopathic headache disorders (group 4 of the IHS classification) - Report of an EFNS task force

Evers

Goadsby

Jensen

et al. 2011

European Journal of Neurology

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Background and Purpose: Certain miscellaneous idiopathic headache disorders, which are regarded as entities, are grouped in chapter 4 of the International Classification of Headache Disorders. Recent epidemiological research suggests that these headache disorders are underdiagnosed. Objectives: To give expert recommendations for the different drug and non-drug treatment procedures of these different headache disorders based on a literature search and on consensus of an expert panel. Methods: All available medical reference systems were screened for all kinds of clinical studies on these headache disorders. The findings in these studies were evaluated according to the recommendations of the EFNS resulting in level A, B or C recommendations and good practice points. Recommendations: For all headache disorders, acute and prophylactic drug treatment is recommended based on case series and on expert consensus. Furthermore, recommendations for the differential diagnoses are given because these headache disorders can also present with a symptomatic form. The most effective drug for the majority of these headache disorders is indomethacin, mostly applied as long-term or short-term prophylaxis.

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“…Primary TCH generally responds poorly to analgesics. In one report, a woman with an apparent primary TCH had frequent recurrences of the headache until she reached (by day 14) a therapeutic dosage of gabapentin 600 mg three times a day [ 85 ]. The exact mechanism of action through which gabapentin decreases headache pain is not known, although multiple mechanisms might be involved.…”

Section: The Treatmentmentioning

confidence: 99%

Focus on the management of thunderclap headache: from nosography to treatment

Ferrante

Tassorelli

Rossi³

et al. 2011

J Headache Pain

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Thunderclap headache (TCH) is an excruciating headache characterized by a very sudden onset. Recognition and accurate diagnosis of TCH are important in order to rule out the various, serious underlying brain disorders that, in a high percentage of cases, are the real cause of the headache. Primary TCH, which may recur intermittently and generally has a spontaneous, benign evolution, can thus be diagnosed only when all other potential underlying causes have been excluded through accurate diagnostic work up. In this review, we focus on the management of TCH, paying particular attention to the diagnostic work up and treatment of the condition.

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Persistent primary thunderclap headache responsive to gabapentin

Cited by 9 publications

References 8 publications

Is gabapentin an effective treatment choice for hemicrania continua?

Is gabapentin an effective treatment choice for hemicrania continua?

Treatment of miscellaneous idiopathic headache disorders (group 4 of the IHS classification) - Report of an EFNS task force

Focus on the management of thunderclap headache: from nosography to treatment

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