Persistent racial disparities in deep brain stimulation for Parkinson’s disease

Cramer, Samuel W.; Truong, Huy Q.; Palzer, Elise F; Naik, Anant; Rice, Abigail L; Novy, Savannah G; Hanson, Jacob; Howard, Madeleine A; Huling, Jared D.; Chen, Clark C.; McGovern, Robert A.

doi:10.1101/2022.04.05.22273075

Cited by 2 publications

(9 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our current review found a gender disparity (Hariz and Hariz, 2000;Setiawan et al, 2006;Willis et al, 2014;Shpiner et al, 2019;Cramer et al, 2022;Deshpande et al, 2022;Jost et al, 2022;Watanabe et al, 2022) and suggested that the proportion of male patients undergoing STN DBS appears to exceed the reported 1.48: 1 male-tofemale ratio among patients with PD (Katz et al, 2011;Moisan et al, 2016;Shpiner et al, 2019). Three research studies sought to elucidate the factors underlying the observed gender disparity.…”

Section: Gender Disparitymentioning

confidence: 73%

“…Our review revealed that the availability of DBS among Black individuals is lower (Chan et al, 2014;Willis et al, 2014;Cramer et al, 2022;Dorritie et al, 2023;Skelton et al, 2023). Table 2 provides details of the included studies.…”

Section: Racial Disparitymentioning

confidence: 92%

“…Other investigations aimed to assess whether racial disparities in DBS utilization for PD have improved over time (Cramer et al, 2022). One study utilized the NIS data spanning from 2002 to 2018.…”

Section: Racial Disparitymentioning

confidence: 99%

“…The findings in this comprehensive review confirm that DBS is often underutilized among Black patients and other racial minorities with PD. Moreover, the racial disparity in DBS utilization has remained relatively unchanged over the past decade (Cramer et al, 2022), with most data focusing on Black and White populations collected exclusively in the US, and there is no available data on other races. While most studies conducted thus far have focused on identifying the existence of this disparity, only a few have delved into the underlying causes and factors contributing to this phenomenon.…”

Section: Racial Disparitiesmentioning

confidence: 99%

“…It is important to note that comorbidities do not appear to be the underlying factor contributing to the racial disparity in DBS utilization (Cramer et al, 2022). Black patients with PD tend to under-report motor symptoms and receive diagnoses later in their illness, often perceiving PD as a natural part of aging and thus being less inclined to seek treatment (Dahodwala et al, 2011).…”

Section: Racial Disparitiesmentioning

confidence: 99%

See 4 more Smart Citations

A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease

Memon,

Gelman,

Melott

et al. 2023

Front. Hum. Neurosci.

View full text Add to dashboard Cite

BackgroundDeep brain stimulation (DBS) is the primary surgical intervention for Parkinson’s disease (PD) patients with insufficient response to medication, significantly improving motor symptoms and quality of life. Despite FDA approval for over two decades, access to this therapy remains limited. This systematic review aims to evaluate the influence of gender, race/ethnicity, socioeconomic status, and age on health disparities associated with DBS for PD, providing an overview of current research in this field.MethodsA systematic literature search was conducted in PubMed/MEDLINE, Embase, Web of Science and Cochrane databases from 1960 to September 12th, 2023, following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Studies that examine the disparities in accessing DBS among patients with PD were included, comparing different demographic factors. Findings were synthesized and presented narratively to identify and understand DBS disparities.ResultsAfter screening for relevance, 25 studies published between 1960 and 2023 were included, with 16 studies meeting full-text review criteria. While reviewing the references of the 16 articles, two additional studies were included, bringing the total number of included studies to 18. Most studies originated from the United States (44%). The identified studies were categorized as identifying disparities, understanding disparities, or reducing disparities. The majority focused on identifying disparities (72%), while fewer studies delved into understanding the underlying factors (28%). No studies evaluated strategies for reducing disparities. The findings indicate that elderly, female, and Black people, as well as those from low socioeconomic backgrounds and developing countries face greater obstacles in accessing DBS for PD.ConclusionThis study highlights factors contributing to disparities in DBS utilization for PD, including race, gender, and socioeconomic status. Public health policymakers, practitioners, and clinicians should recognize these inequalities and work toward reducing disparities, particularly among vulnerable populations.

show abstract

Section: Gender Disparitymentioning

confidence: 73%

Section: Racial Disparitymentioning

confidence: 92%

Section: Racial Disparitymentioning

confidence: 99%

Section: Racial Disparitiesmentioning

confidence: 99%

Section: Racial Disparitiesmentioning

confidence: 99%

See 3 more Smart Citations

A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease

Memon,

Gelman,

Melott

et al. 2023

Front. Hum. Neurosci.

View full text Add to dashboard Cite

show abstract

Rewriting the Script: the Need for Effective Education to Address Racial Disparities in Transcranial Magnetic Stimulation Uptake in BIPOC Communities

Sullivan,

Henry,

Lehman

et al. 2024

Neuroethics

View full text Add to dashboard Cite

Depression is a widespread concern in the United States. Neuromodulation treatments are becoming more common but there is emerging concern for racial disparities in neuromodulation treatment utilization. This study focuses on Transcranial Magnetic Stimulation (TMS), a treatment for depression, and the structural and attitudinal barriers that racialized individuals face in accessing it. In January 2023 participants from the Twin Cities, Minnesota engaged in focus groups, coupled with an educational video intervention. Individuals self identified as non-white who had no previous TMS exposure but had tried at least one treatment for their depression. Results revealed that the intervention did not notably change knowledge or stigma about TMS, but attitudes surrounding traveling for treatment changed. Notably, barriers like affordability, frequency of treatment, and lack of knowledge persist. Participants expressed a desire for more information, personal connection, and a tailored educational approach. The study suggests a need for multifaceted strategies to reduce disparities, focusing on education, community-based resources, and policy interventions. Immediate actions that can be taken include the creation of a TMS education program focused on patient engagement and awareness about TMS.

show abstract

Persistent racial disparities in deep brain stimulation for Parkinson’s disease

Cited by 2 publications

References 40 publications

A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease

A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease

Rewriting the Script: the Need for Effective Education to Address Racial Disparities in Transcranial Magnetic Stimulation Uptake in BIPOC Communities

Contact Info

Product

Resources

About