Persistent severe gastrointestinal bleeding in a man with metastatic somatostatinoma

Musumba, Crispin; Usman-Saeed, Muniba; O'Toole, P.A.; Powell, Steven; Smart, Howard

doi:10.1136/gutjnl-2011-300939

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2013

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“…Interestingly, this patient presented with acute massive gastric haemorrhage, which was a rare manifestation of this tumor. Duodenal and periampullary bleeding have been reported in very few cases worldwide as a clinical presentation 10-12. The bleeding was easily stopped with an adrenaline injection.…”

Section: Discussionmentioning

confidence: 99%

Gastric Somatostatinoma: An Extremely Rare Cause of Upper Gastrointestinal Bleeding

Prachayakul

Aswakul²,

Deesomsak³

et al. 2013

Clin Endosc

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A 49-year-old woman presented with chronic abdominal discomfort, significant weight loss, and chronic intermittent diarrhea. She suddenly developed massive upper gastrointestinal bleeding and was referred for further treatment. Endoscopy indicated a large mass in the upper gastric body with antral and duodenal bulb involvement. Endosonography showed a large well-defined isoechoic gastric subepithelial mass with multiple intra-abdominal and peripancreatic lymphadenopathy, suspected to be malignant on the basis of fine needle aspiration cytology. The tumor was surgically removed, and histopathology showed typical characteristics of a neuroendocrine tumor. On the basis of immunohistochemical staining, somatostatinoma, a rare neuroendocrine tumor, was diagnosed. Gastrointestinal bleeding is a rare presentation and the stomach is an uncommon tumor location.

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Section: Discussionmentioning

confidence: 99%