2022
DOI: 10.1016/j.idc.2022.04.004
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Persistent Symptoms After Treatment of Lyme Disease

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Cited by 13 publications
(9 citation statements)
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“…Some patients report having persistent or relapsing nonspecific symptoms (e.g. arthralgia, myalgia, fatigue) after completing treatment for Lyme disease, which is referred to as posttreatment Lyme disease syndrome (PTLDS) if it lasts for at least 6 months and is associated with some degree of functional impairment, a subset of what is sometimes termed ‘chronic Lyme disease’ [12,13 ▪▪ ]. There is no accepted clinical definition as to what constitutes ‘chronic Lyme disease’, and the term is frequently applied to a highly heterogeneous group of patients, including many with no objective evidence of ever having had Lyme disease [7].…”
Section: Bacterial Infectionsmentioning
confidence: 99%
“…Some patients report having persistent or relapsing nonspecific symptoms (e.g. arthralgia, myalgia, fatigue) after completing treatment for Lyme disease, which is referred to as posttreatment Lyme disease syndrome (PTLDS) if it lasts for at least 6 months and is associated with some degree of functional impairment, a subset of what is sometimes termed ‘chronic Lyme disease’ [12,13 ▪▪ ]. There is no accepted clinical definition as to what constitutes ‘chronic Lyme disease’, and the term is frequently applied to a highly heterogeneous group of patients, including many with no objective evidence of ever having had Lyme disease [7].…”
Section: Bacterial Infectionsmentioning
confidence: 99%
“…Fatigue, joint and muscle pain, difficulties with memory and concentration, and sleep and mood disturbances are the most common post‐treatment Lyme disease symptoms. The mechanisms underlying these symptoms are unknown, and it is likely that different factors play a role in an individual case 23 . There is hope that Long COVID research could help to identify the mechanisms underlying persistent symptoms after Lyme disease and facilitate the development of diagnostics and treatments for this underserved community as well.…”
Section: Lessons Learned From Other Post‐infectious Complicationsmentioning
confidence: 99%
“…The clinical presentation of Lyme disease can range from a rash at the site of the tick bite accompanied by flu‐like symptoms to more severe manifestations including arthritis, nervous system disease and carditis (CDC, 2022b). Although most patients who contract LD fully recover after antibiotic treatment, some patients have persistent non‐specific symptoms lasting more than 6 months (Marques, 2022). The annual economic impact of LD in the United States is estimated to range from $355–968 million USD (Hook, Jeon, et al., 2022).…”
Section: Introductionmentioning
confidence: 99%