Persistent Wheeze in Infants: A Guide for General Pediatricians

Yu, Yolanda A; Esther, Charles R.; Ren, Clement L.; Loughlin, Ceila E.

doi:10.3928/19382359-20190222-02

Cited by 1 publication

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“…Differential diagnosis of wheezing is important and will increase the success of the treatment, and also has an important role in the follow-up of the cases. In patients who do not respond to the treatment, tuberculosis, cystic fibrosis, congenital lung malformations and congenital heart diseases should be considered in the differential diagnosis (11,12). In our study, cases with treatment failure were evaluated for possible etiological factors and patients with additional diseases were excluded from the study.…”

Section: Discussionmentioning

confidence: 99%

Etiological Evaluation of Infants with Wheezing

Şen¹,

Bostancı²,

Özmen³

2021

eamr

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INTRODUCTION:Patients with recurrent wheezing should be evaluated for asthma and the differential diagnosis should be made carefully. The aim of this study was to evaluate the demographic and etiological characteristics of patients presenting with recurrent wheezing under 3 years of age. METHODS: Ninety-two wheezy children were consequently enrolled in this study at the outpatient clinic of Dr Sami Ulus Maternity, Children's and Diseases Training and Research Hospital, Ankara, Turkey between March 2009 and March 2010. Demographic characteristics, number of attacks in the last year, the number of hospitalizations, eosinophils were recorded. RESULTS: The mean age of 92 patients was 19.9 + -9.4 months and the youngest patient was 6 months. Seventy of the cases were male. The etiologic evaluation of the cases was as follows: 42 patients with atopic wheezing, 28 patients with gastroesophageal reflux and 23 patients with viral induced wheezing. Eosinophilia was not statistically significant in patients with presence of atopy in family members (18 patient) compared to those without familial atopy history. DISCUSSION AND CONCLUSION: In our study the most common etiological factor is atopy and it is followed by gastroesophageal reflux and viral agents, respectively. The definition of wheezing children includes diseases with different pathophysiology, course and prognosis. Children with nonatopic wheezing may develop chronic inflammation in the lungs similar to asthma. It is necessary to differentiate these diseases in the early period and to make the follow-up and treatment approaches correctly. Produced from the thesis titled ''Is there a diagnostic value of high-sensitivity C-reactive protein in wheezing infants?''.

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Section: Discussionmentioning

confidence: 99%