Person-related work and incident use of antidepressants: relations and mediating factors from the Danish work environment cohort study

Madsen, Ida E. H.; Diderichsen, Finn; Burr, Hermann; Rugulies, Reiner

doi:10.5271/sjweh.3049

Cited by 55 publications

(57 citation statements)

References 59 publications

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“…Some studies based on non-self reported measures have shown a relation between psychological demands and depression (10,12,14), and some have shown a relation between other measures of psychosocial working conditions and depression (15,17,40,41). The few studies investigating non-self-reported measures of decision latitude have found no statistically significant results (10,16,18).…”

Section: Discussionmentioning

confidence: 91%

A two-year follow-up study of risk of depression according to work-unit measures of psychological demands and decision latitude

Grynderup

Mors²,

Hansen³

et al. 2012

Scand J Work Environ Health

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Biased reporting of working conditions may inflate associations with depression. We examined the risk of depression among employees of small work units with homogenous working conditions experiencing low and high levels of psychological demands and decision latitude. We observed no strong associations. Control over own work or reduced work demands as a means to prevent depression is therefore not supported.

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Section: Discussionmentioning

confidence: 91%

A two-year follow-up study of risk of depression according to work-unit measures of psychological demands and decision latitude

Grynderup

Mors²,

Hansen³

et al. 2012

Scand J Work Environ Health

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“…The study by Nielsen et al (44) was from Denmark and two previous studies from this country showed that poor job climate predicted risk of hospitalization for depression (52) but not purchase of antidepressants (53), indicating that antidepressant purchase may be a problematic measure for onset of depression. However, other studies from Denmark reported that psychosocial work environment factors, such as high emotional demands (54), high quantitative demands (55), low workplace social support (55), and high job insecurity (56) predicted purchase of antidepressants, suggesting the usefulness of antidepressant purchase as an indicator for depressive disorders in psychosocial occupational health studies. Based on these conflicting results, we can neither confirm nor reject that the divergent estimate by Nielsen et al (44) was specific to the use of antidepressant purchase as the outcome measure.…”

Section: Summary Of Evidencementioning

confidence: 99%

Effort–reward imbalance at work and risk of depressive disorders. A systematic review and meta-analysis of prospective cohort studies

Rugulies

Aust²,

Madsen³

2017

Scand J Work Environ Health

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278

204

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Effort-reward imbalance at work and risk of depressive disorders. A systematic review and meta-analysis of prospective cohort studies by Rugulies R, Aust B, Madsen IEH Effort-reward imbalance at work predicted a 1.5-fold increased risk of depressive disorders in this systematic review and meta-analysis of eight prospective cohort studies from Europe, Canada and the USA. This study provides the hitherto strongest evidence for a possible role of effort-reward imbalance in the etiology of depressive disorders. Review Scand J Work Environ Health. 2017;43(4):294-306. doi:10.5271/sjweh.3632 Effort-reward imbalance at work and risk of depressive disorders. A systematic review and meta-analysis of prospective cohort studies Objective The aim of this review was to determine whether employees exposed to effort-reward imbalance (ERI) at work have a higher risk of depressive disorders than non-exposed employees. AffiliationMethods We conducted a systematic review and meta-analysis of published prospective cohort studies examining the association of ERI at baseline with onset of depressive disorders at follow-up. The work was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and a detailed study protocol was registered before literature search commenced (Registration number: CRD42016047581). We obtained a summary estimate for the association of ERI with risk of depressive disorders by pooling the study-specific estimates in a meta-analysis. We further conducted pre-defined sensitivity analyses.Results We identified eight eligible cohort studies, encompassing 84 963 employees and 2897 (3.4%) new cases of depressive disorders. Seven of the eight studies suggested an increased risk of depressive disorders among employees exposed to ERI. The pooled random-effects estimate was 1.49 [95% confidence interval (95% CI) 1.23-1.80, P<0.001], indicating that ERI predicts risk of depressive disorders. The estimate was robust in sensitivity analyses stratified by study quality, type of ERI ascertainment and type depressive disorder ascertainment, respectively. Conclusions Employees exposed to ERI were at increased risk of depressive disorder. Future studies on ERI and depressive disorders should examine if this association is stronger or weaker when ERI is measured repeatedly during follow-up and with other methods than self-report or when depressive disorders are ascertained with clinical diagnostic interviews.

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“…In addition to psychosocial stressors, work arrangements such as long working hours [8] or having an insecure job [9] have been associated with mental health problems. Furthermore, mental health problems have been found to be more common in lower socioeconomic groups [10] and a high prevalence of mental health problems has been observed in certain occupations within health and welfare services [11][12][13] suggesting that physical working conditions may also be relevant to mental health problems.…”

Section: Introductionmentioning

confidence: 99%

Working conditions and psychotropic medication: a prospective cohort study

Laaksonen

Lallukka

Lahelma

et al. 2011

Soc Psychiatry Psychiatr Epidemiol

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Person-related work and incident use of antidepressants: relations and mediating factors from the Danish work environment cohort study

Cited by 55 publications

References 59 publications

A two-year follow-up study of risk of depression according to work-unit measures of psychological demands and decision latitude

A two-year follow-up study of risk of depression according to work-unit measures of psychological demands and decision latitude

Effort–reward imbalance at work and risk of depressive disorders. A systematic review and meta-analysis of prospective cohort studies

Working conditions and psychotropic medication: a prospective cohort study

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