The article is devoted to the problem of humanitarian control of interactions in modern technological culture. Particular attention is paid to the technology of information manipulation, the relationship of digital culture and the individual lifeworld. The objectives of the article include identification of the specifics of interacting subjects in information environments, clarifying the principles of their design in the network order. The need is stressed for a civilizational approach that emphasizes the relevance of ethical relationship as the basis for the humanitarian control over the design of interactions in technogenic environments. Nowadays, civilization is interpreted as a "society of knowledge" that unites the components of the technosphere and the political, ethical, cultural, mental aspects of social life. The study is conducted in terms of the interdisciplinary approach, in which context any object is treated as a sociotechnical one, included into the communication environment and into the system of subject interactions. The article specifies the methods of subject interactions design in information environments. The practical aspect of interactions designing technology is demonstrated in the process of making optimal decisions when a new product is created. The main conclusion is that in the network space, the interaction of human and technology should be considered from the standpoint of partner relations.