Personal Technique of Microinfiltration With Botulin Toxin: The SINB Technique (Superficial Injection Needling Botulinum)

Abstract

The superficial injection needling botulinum (SINB) technique is the dermal injection of microdoses of botulin toxin, not by traditional syringe but with needling technique that consists in multiple microdroplets by electrical device. The intention is to decrease sweat and sebaceous gland activity to improve skin texture and sheen and to target the superficial layer of muscles that find attachment to the undersurface of the dermis causing visible rhytides. The technique is for treatment of face and neck by the injection of the botulin toxin into the dermis or in subdermal plane to improve skin texture, smoothen horizontal creases, and decrease vertical banding of the neck as well as to achieve better apposition of the platysma to the jawline and neck, improving contouring of the cervicomental angle. The botox solution is hyperconcentrated when compared to traditional dilution or compared to microbotox or mesobotox. Furthermore, the injection technique is different because spreading superficial microdroplets are not performed, but small, homogeneous, and controlled amounts of solution are injected. Each 0.8-mL syringe contains 50 units of onabotulinumtoxinA. The solution is delivered intradermally, using an electrical needling pen and setting the depth penetration of the needles at 3 to 3.5 mm. The 2 conjugated techniques play a 2-fold action on the skin. The technique was applied to a group of 63 patients dealing with face, forehead, cheekbones, and neck.

Management of wide facial pores by topical microbotox with microneedling

“…Calvani et al demonstrated that percutaneous needle pricks themselves have been reported to create several microbruises in the dermis, and they really initiate a complex cascade of growth factors that eventually result in collagen production (1).…”

“…When Calvani et al employed BONT/A in the treatment of neck skin folds and reported that all patients were followed up every month for six months, this explains why All patients had to start again from the beginning after the follow-up period since the benefits had faded entirely (1).…”

Scientific review of the aesthetic uses of botulinum toxin type A

“…Finally, it is worthwhile to mention the use of microdroplets of BoNT-A, also called mesobotox or microbotox, which is the injection maneuver of multiple microinjections of a diluted BoNT-A into the dermis or interface between the dermis and the superficial layer of the facial muscles, glands, and skin structures. The mesobotox procedure is mesotherapy using BoNT as a mesoproduct [ 5 , 31 ]. This emerging technique is considered to be a possible approach for BoNT treatment for facial rejuvenation temporally.…”

“…For instance, it is used to prevent chronic migraine [ 2 , 3 ] and treat neuralgia or peripheral neuropathic pain [ 4 ]. Although the current theoretical basis is insufficient, there are certain medical conditions for which BoNT-A treatment, such as mesobotox, is effective [ 5 ]. However, the theoretical basis can be deduced through an anatomical and pathological analysis of the disease and consideration of the relevant mechanism of action of BoNT-A.…”

Peptídeo Botulínico Novo Protocolo De Tratamento Tegumentar

“…Microbotox ou mesobotox são denominações relacionadas aos protocolos de tratamento com utilização de microdoses de TB associada a micropunturas6,12 . Basicamente, doses de TB reconstituída é diluída com mais quantidade de soro fisiológico 0,9% injetável e o produto final é a TB mais diluída ainda6,14 .…”