“…Acton, 2003;;Ersche, et al, 2010;Moeller et al 2002), openness to experience and extraversion (Grekin, Sher & Wood, 2006), with considerable cross-over across these constructs (Depue & Collins, 1999;Kelly et al, 2006;Sher & Trull, 1994;Zuckerman et al, 1993). For example, some researchers have suggested that extraversion is an indirect test of sensation-seeking (Sher & Trull, 1994), with impulsivity a reconceptualised 'adult' form of sensation-seeking (Clayton, Segress & Caudill, 2007). This poses the question as to whether these constructs are distinct, or if they are in fact best described as a single more unified personality concept of particular relevance to substance use.…”