Personalized Approaches to Stroke: One Step Forward for Functional Recovery of Stroke Patients

Abstract

Recent advances in diagnoses, management, and rehabilitation have had a significant impact to reduce mortality and functional recovery in stroke patients. In spite of these medical advances, many stroke survivors still suffer from significant disabilities. Stroke is a complex disease caused by a combination of multiple risk factors. Therefore, personalized medicine is more important than any other field to overcome the limitations of current stroke management and rehabilitation. It is necessary to apply accurate evaluation for functions and a personalized approach in consideration of various characteristics of each stroke patient to improve function. The objective of this Special Issue is to inform the recent scientific knowledge, current limitations, and challenges for an individually tailored strategy in the areas of diagnosis, treatment, and rehabilitation of stroke. A multidisciplinary approach and research will be strongly encouraged for personalized medicine in the field of stroke treatment and rehabilitation.

A Comprehensive Review on the Role of Resting-State Functional Magnetic Resonance Imaging in Predicting Post-Stroke Motor and Sensory Outcomes

“…Lesion volume or lesion location, age, stroke severity, and comorbid factors may influence stroke outcomes [42][43][44][45][46][47][48], but even mild stroke severity is not enough to provide an accurate prediction of favorable outcomes [49]. Thus, novel prognostic biomarkers are crucial for the development of personalized recovery treatment strategies [50] and the amelioration of patients' and caregivers' quality of life [51]. Brain plasticity remains a crucial issue in stroke rehabilitation, and advances in MRI techniques have the potential to improve the clinical and research opportunities and knowledge in that field.…”

Effect of sonification types in upper-limb movement: a quantitative and qualitative study in hemiparetic and healthy participants

“…Movement sonification devices have many advantages [ 60 ]: access to a continuous 3D auditory information, fast adaptation of sound feedback to the movements performed, flexibility of use by participants with various profiles thanks to possible adaptation according to individual abilities [ 7 , 23 ]. Thus, these devices present a potential added value in comparison with other sound/musical methods and tools, and offer perspectives in adequacy with the needs described in the rehabilitation framework [ 12 , 66 ]. Moreover, compared to other feedback modalities such as visual feedback, the use of the auditory modality does not constrain the user's posture.…”