Personalized Lifestyle Medicine: Relevance for Nutrition and Lifestyle Recommendations

Minich, Deanna M.; Bland, Jeffrey

doi:10.1155/2013/129841

Cited by 77 publications

(53 citation statements)

References 81 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Population-based health recommendations have limited efficacy in promoting health behavioral changes [1,2,3]. This may be due to individual differences in responding to dietary changes because of nutrient-gene interactions [2].…”

Section: Introductionmentioning

confidence: 99%

An Intervention Study of Individual, apoE Genotype-Based Dietary and Physical-Activity Advice: Impact on Health Behavior

et al. 2014

View full text Add to dashboard Cite

Aim: To assess the behavioral effects of receiving personal genetic information, using apoE genotypes as a tool for promoting lifestyle changes. apoE was chosen because it has a significant impact on lipid metabolism and cholesterol absorption, both factors in cardiovascular disease. Methods: This study was a 1-year intervention study of healthy adults aged 20-67 years (n = 107). Their behavioral changes were measured by diet (e.g., fat quality, as well as consumption of vegetables, berries, fruits, and fatty and sugary foods), alcohol consumption, and exercise. Health and taste attitudes were assessed with the Health and Taste Attitude Scales (HTAS). The measurements were performed 4 times: at baseline (T0), as well as 10 weeks (T1), 6 months (T2), and 12 months after baseline (T3). These behavioral effects were assessed for three groups: a high-risk (Ɛ4+; n = 16), a low-risk (Ɛ4-; n = 35), and a control group (n = 56). Results: Personal genetic information affected health behavior. Dietary fat quality improved more in the Ɛ4+ group than in the Ɛ4- and control groups after personal, genotype-based health advice. This change differed significantly between the Ɛ4+ and the control group (p < 0.05), but only for a short time. Conclusion: Personal genetic information, based on apoE, may affect dietary fat quality. More research is required to determine how to utilize genotype-based health information and how to efficiently achieve long-term changes in the prevention of lifestyle-related diseases.

show abstract

Section: Introductionmentioning

confidence: 99%

An Intervention Study of Individual, apoE Genotype-Based Dietary and Physical-Activity Advice: Impact on Health Behavior

et al. 2014

View full text Add to dashboard Cite

show abstract

“…The principal objective of PM about nutrition is to render the efficacious approach to manage diseases with totally dependent on "the genetics, lifestyle (dietary, exercise and lifestyle choices), metabolic status, gut microbiota and physiological status (nutrient level and disease status)" of any patient without any bad outcome 126 . It has been reported that multiple chronic hereditary metabolic clinical problems can be adequately managed in precision nutritional care [127][128][129] . Three most significant areas need to measure in precision nutrition that comprises discrete principles for adequate nutritional "status, biomarker monitoring or techniques for nutrient detection and the applicable therapeutic or intervention methods" 126 .…”

Section: Nutritional Diseases and Precision Medicinementioning

confidence: 99%

Prospects and Challenges of Precision Medicine in Lower- and Middle-Income Countries: A Brief Overview

Haque

Islam

Sartelli

et al. 2019

Bangladesh J Med Sci

View full text Add to dashboard Cite

The trend of NCDs in most LMIC countries is slowly but gradually follows that of in the developed countries. There are four significant diseases reported by WHO, which are equally common, such as CVDs, diabetes, cancer, and chronic respiratory disease that causes widespread early death & morbidity. Indeed, it incurs an overwhelming financial burden to most countries in the world. The rise of drug-resistant microbes is another major problem. To overcome this issue, precision medicine (PM) comes into play whereby individual variability in genes, environment, lifestyle, and nutrition of each person is considered for disease treatment & prevention. PM provides a personalized approach, the right treatment to the right people at the right time. Many wealthy countries in the West have started adopting PM though the initial cost is high, ultimately, in the long run, will reduce the healthcare cost by getting rid of the ineffective treatment strategies. However, the PM in LMICs is still at an early stage due to issues such as lack of populationspecific data, competency, expertise, and poor financial support. Bangladesh Journal of Medical Science Vol.19(1) 2020 p.32-47

show abstract

“…Furthermore, a polymorphism within the MPO gene (rs2333227) is associated with hypertension [60] and cancer risk, with the latter genetic relationship being mitigated through diet [61]. Conversely the association between plasma levels of MPO and hypertension is strengthened in the presence of hyperglycemiainduced oxidative stress, which could be targeted in a personalized nutritional program [62,63].…”

Section: Metabolomics the Gut Microbiome And Nutrigeneticsmentioning

confidence: 99%

Personalized Hypertension Management in Practice

Gladding

Patrick²,

Manley³

et al. 2015

Per. Med.

View full text Add to dashboard Cite

The revolution occurring in genomic and personalized medicine is likely to have a significant impact on the management of hypertension. However, from the perspective of translating new knowledge into clinical practice, progress has been slow. This review article summarizes recent advances in hypertension-related diagnostics while also offering new perspective on hypertension management for the future. Such new perspectives will likely require a paradigm shift toward more integrated and holistic approaches for better prevention and treatment of hypertension in both individuals and the population as a whole.

show abstract

Personalized Lifestyle Medicine: Relevance for Nutrition and Lifestyle Recommendations

Cited by 77 publications

References 81 publications

An Intervention Study of Individual, apoE Genotype-Based Dietary and Physical-Activity Advice: Impact on Health Behavior

An Intervention Study of Individual, apoE Genotype-Based Dietary and Physical-Activity Advice: Impact on Health Behavior

Prospects and Challenges of Precision Medicine in Lower- and Middle-Income Countries: A Brief Overview

Personalized Hypertension Management in Practice

Contact Info

Product

Resources

About