Personalized Physiological Medicine as the Future of Intensive Care Medicine

The Human Microbiome in Intensive Care - A Journey Forward?

“…Few studies address microbiota in ICU patients, and even fewer link microbiota to personalized medicine, whose importance in the ICU may be key to the future treatment of critically ill patients [ 12 , 13 ]. The link may be mediated through inflammatory markers (oxygen and nitrogen reactive species, cytokines with genetic polymorphisms that modulate immune response in sepsis and chemokines), metabolites (especially microbial branched-chain amino acids), and gene toxicity [ 14 , 15 ].…”