Novel Aspects of Gas Chromatography and Chemometrics 2023
DOI: 10.5772/intechopen.110591
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Perspective Chapter: Negative Thermal Gradient Gas Chromatography

Abstract: Gas chromatography is typically operated in isothermal mode for optimum separation of a mixture of compounds with a narrow boiling point range, or in temperature-programmed mode, which strives to achieve a compromise between separation efficiency and time. Temperature gradients also keep the peak widths nearly constant over a wide range of retention times, enhancing the detectability of the later eluting peaks. In this chapter, the use of negative thermal gradients for gas chromatography (NTGGC) – for the sake… Show more

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