Perspective on non-invasive and non-destructive photoacoustic and photothermal applications

Glorieux, Christ

doi:10.1063/5.0091261

Cited by 7 publications

(3 citation statements)

References 173 publications

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“…BRRT-CT-5032), non-destructive testing by laser ultrasonics [44][45][46][47] (EU-ITN project NDTonAIR [48]. Recently the first footsteps were made in the field of elastic characterization of biological cells and tissue, and photoacoustic imaging [49,50], in a perspective of using this approach for biomedical applications. A nice synergy between physics and arts was evidenced by the outcome of a collaboration between the laboratory and artist Aernoudt Jacobs, in the form of the artworks Photophone" [51] and "Heliophone" [51,52], in the framework of an IWT CICI-grant (2013-2015).…”

Section: Physical Acousticsmentioning

confidence: 99%

History and activities of KU Leuven Laboratory of Acoustics

Glorieux,

Cops,

Vermeir

et al. 2022

Proceedings of the 10th Convention of the European Acoustics Association Forum Acusticum 2023

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The Laboratory of Acoustics at KU Leuven was founded more than 50 years ago. Till today, a variety of acoustics related topics, ranging from physical acoustics, through building and room acoustics up to environmental acoustics and noise related health issues, has been investigated. In the second half of the 20th century, the laboratory was one of the main centers of expertise in acoustics in Belgium, which contributed to consulting and the establishment of legislation in building and environmental acoustics. In the 1990's it also consolidated expertise on the characterization of porous materials and was one of the driving research groups in the field of photoacoustics. During the past 15 years, additional research directions have been taken thanks to interdisciplinary collaborations, including psychoacoustics, perception of sound, sound quality assessment, archaeo-acoustics, tackling acoustic issues in building retrofit, and characterisation of walls materials in the framework of sustainable development (recycled materials, biomaterials etc.) This paper first brings a brief historical overview of activities of ATF performed in the past, its involvement in national and international collaborations and its main recent scientific and educational activities.

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Section: Physical Acousticsmentioning

confidence: 99%

History and activities of KU Leuven Laboratory of Acoustics

Glorieux,

Cops,

Vermeir

et al. 2022

Proceedings of the 10th Convention of the European Acoustics Association Forum Acusticum 2023

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show abstract

“…[23][24][25][26] Over the past two decades, PA imaging has been widely explored for diagnostic imaging 27,28 and nondestructive material evaluation. 29,30 Several past studies utilized PA guidance for US focusing. [31][32][33] However, these studies used the PA guidance to focus the US onto a focal point.…”

Section: Introductionmentioning

confidence: 99%

“…The US waves thus generated can be sensed using ultrasonic transducers and the collected signals can be further processed to facilitate structural and functional imaging 23–26 . Over the past two decades, PA imaging has been widely explored for diagnostic imaging 27,28 and nondestructive material evaluation 29,30 …”

Section: Introductionmentioning

confidence: 99%

Feasibility of photoacoustic‐guided ultrasound treatment for port wine stains

et al. 2022

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Background and Objectives: Port wine birthmark, also known as port wine stain (PWS) is a skin discoloration characterized by red/purple patches caused by vascular malformation. PWS is typically treated by using lasers to destroy abnormal blood vessels. The laser heating facilitates selective photothermolysis of the vessels and attenuates quickly in the tissue due to high optical scattering. Therefore, residual abnormal capillaries deep in the tissue survive and often lead to the resurgence of PWS. Ultrasound (US) has also been proposed to treat PWS, however, it is nonselective with respect to the vasculature but penetrates deeper into the tissue. We aim to study the feasibility of a hybrid PWS treatment modality combining the advantages of both modalities. Materials and Methods: In this manuscript, we propose a photoacoustic (PA) guided US focusing methodology for PWS treatment which combines the optical contrast-based selectivity with US penetration to focus the US energy onto the vasculature. The PA signals collected by the transducers, when time-reversed, amplified, and transmitted, converge onto the PWS, thus minimally affecting the neighboring tissue. We performed two-and three-dimensional simulations that mimic realistic transducers and medium properties in this proof of concept study. Results: The time-reversed PA signals when transmitted from the transducers converged onto the vasculature, as expected, thus reducing the heating of the neighboring tissue. We observed that while the US focus is indeed affected due to experimental factors such as limited-view, large detector separation and finite detection bandwidth, and so forth, the US did focus completely or partially onto the vasculature demonstrating the feasibility of the proposed methodology. Conclusion:The results demonstrate the potential of the proposed methodology for PWS treatment. This treatment method can destroy the deeper capillaries while minimally heating the neighboring tissue, thus reducing the chances of the resurgence of PWS and as well as cosmetic scarring.K E Y W O R D S photoacoustic (PA)-guided ultrasound (US), photoacoustics (PA), port wine stain (PWS), time-reversal (TR), high-intensity focused ultrasound (HIFU)

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Editorial for the special collection on non-invasive and non-destructive methods and applications, I: Festschrift—A tribute to Andreas Mandelis

Gusev

Franko

2022

Journal of Applied Physics

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Perspective on non-invasive and non-destructive photoacoustic and photothermal applications

Cited by 7 publications

References 173 publications

History and activities of KU Leuven Laboratory of Acoustics

History and activities of KU Leuven Laboratory of Acoustics

Feasibility of photoacoustic‐guided ultrasound treatment for port wine stains

Editorial for the special collection on non-invasive and non-destructive methods and applications, I: Festschrift—A tribute to Andreas Mandelis

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