Perspective on pre- and post-natal agro-food exposure to persistent organic pollutants and their effects on quality of life

Fernández-Cruz, Tania; Elena, María; Simal‐Gándara, Jesús

doi:10.1016/j.envint.2017.01.001

Cited by 35 publications

(13 citation statements)

References 181 publications

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“…It is therefore important to make patients know that preferring organic food could have a real benefice for reproduction. In addition, a recent review, showed that, peeling fruits and vegetable, can reduce pesticide residues more effectively than washing and soaking [ 34 ], it could therefore be worth transmitting this message to patients.…”

Section: Discussionmentioning

confidence: 99%

Environmental Health in Perinatal and Early Childhood: Awareness, Representation, Knowledge and Practice of Southern France Perinatal Health Professionals

Sunyach

Antonelli

Tardieu

et al. 2018

IJERPH

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The exposure of adults of reproductive age as well as pregnant women and children to environmental contaminants is of particular concern, as it can impact fertility, in utero development, pregnancy outcomes and child health. Consequently, the World Health Organisation (WHO) and international societies advocate including Environmental Health (EH) in perinatal care, yet perinatal health professionals (HPs) hardly put these recommendations into practice. In 2017, a cross-sectional study was performed in a large panel of perinatal HPs in south-eastern France with the aim of painting a picture of their current attitudes, representation, knowledge, and training expectations. Quantitative and qualitative information was collected via auto-questionnaire. Questionnaires were completed by 962 participants, mainly midwives (41.1%), physicians (25.6%) and nursery nurses (11%). Indoor/outdoor air quality and endocrine disruptors were the best-mastered topics, whereas electromagnetic fields and diet gave rise to unsure responses. Overall, perinatal HPs were ill-trained and -informed about the reproductive risks linked to daily environmental exposure. HPs reported scarce knowledge, fear of patient reaction and lack of solutions as the main barriers to providing information regarding EH to the public. Our findings highlight the need to set up EH training programmes focused on scientific knowledge and to provide simple messages and tips to help perinatal HPs deliver advice to populations to mitigate exposure to environmental toxicants.

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Section: Discussionmentioning

confidence: 99%

Environmental Health in Perinatal and Early Childhood: Awareness, Representation, Knowledge and Practice of Southern France Perinatal Health Professionals

Sunyach

Antonelli

Tardieu

et al. 2018

IJERPH

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“…An increasing number of studies have addressed the concern that environmental pollutants may contribute to the early origin of diseases [38][39][40]. Our findings show that mothers' knowledge that meconium could provide information about the potential of their child being at risk of developing adverse health outcomes would enhance their participation in a meconium study.…”

Section: Advances In Public Healthmentioning

confidence: 71%

Perceptions, Practices, and Mother’s Willingness to Provide Meconium for Use in the Assessment of Environmental Exposures among Children in Mukono and Pallisa Districts, Uganda

Ssempebwa

Musinguzi

Kibira

2018

Advances in Public Health

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Presence of biomarkers or metabolites is assessed in various human biospecimens including meconium in the investigation of exposures to environmental contaminants. This study gathered data on the perceptions and practices of mothers in two rural districts of Uganda concerning meconium and their willingness to provide meconium from their babies for research purposes. The study reveals a wide range of perceptions and beliefs around meconium as well as a number of associated taboos and practices. Many participants noted that meconium could be used to detect ailments among newborns based on its appearance. Practices and beliefs included using it to prevent stomach discomfort and other ailments of newborns, as a means to confirm paternity and initiate the child into the clan as well as facilitating father-child bonding that included ingestion of meconium by the fathers. Most mothers indicated scepticism in accepting to provide meconium for research purposes and had fears of unscrupulous people disguising as researchers and using meconium to harm their children. However, some were willing to provide meconium, if it helped to detect ailments among their children. These perceptions and practices may negatively influence mothers' willingness to participate in meconium study. However, through provision of educational and behaviour change interventions, mothers' willingness to participate in a meconium study can be improved.

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“…Exposure to POPs is widespread through environmental pollutants, daily used cosmetics, daily used items, or food. Importantly, POPs can be transferred from the mother to the child prenatally through the placenta [97] or postnatally by secreting into breast milk [98]. Therefore, prenatal and postnatal exposure to POPs may have many adverse health effects on the immune system and the reproductive system and may be related to other diseases such as cancer, diabetes, and obesity or to adverse pregnancy outcomes [98].…”

Section: Environmental Toxicant Exposure and Neurodevelopmental DImentioning

confidence: 99%

“…Importantly, POPs can be transferred from the mother to the child prenatally through the placenta [97] or postnatally by secreting into breast milk [98]. Therefore, prenatal and postnatal exposure to POPs may have many adverse health effects on the immune system and the reproductive system and may be related to other diseases such as cancer, diabetes, and obesity or to adverse pregnancy outcomes [98]. Moreover, since it is well-known that thyroid hormones are essential for neurodevelopment, prenatal and postnatal exposure to POPs could lead to neurobehavioral problems in children [99].…”

Section: Environmental Toxicant Exposure and Neurodevelopmental DImentioning

confidence: 99%

Neurodevelopmental Disorders and Environmental Toxicants: Epigenetics as an Underlying Mechanism

Tran

Miyake

2017

International Journal of Genomics

123

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The increasing prevalence of neurodevelopmental disorders, especially autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research into the identification of etiologic and risk factors. The Developmental Origin of Health and Disease (DOHaD) hypothesizes that the environment during fetal and childhood development affects the risk for many chronic diseases in later stages of life, including neurodevelopmental disorders. Epigenetics, a term describing mechanisms that cause changes in the chromosome state without affecting DNA sequences, is suggested to be the underlying mechanism, according to the DOHaD hypothesis. Moreover, many neurodevelopmental disorders are also related to epigenetic abnormalities. Experimental and epidemiological studies suggest that exposure to prenatal environmental toxicants is associated with neurodevelopmental disorders. In addition, there is also evidence that environmental toxicants can result in epigenetic alterations, notably DNA methylation. In this review, we first focus on the relationship between neurodevelopmental disorders and environmental toxicants, in particular maternal smoking, plastic-derived chemicals (bisphenol A and phthalates), persistent organic pollutants, and heavy metals. We then review studies showing the epigenetic effects of those environmental factors in humans that may affect normal neurodevelopment.

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Perspective on pre- and post-natal agro-food exposure to persistent organic pollutants and their effects on quality of life

Cited by 35 publications

References 181 publications

Environmental Health in Perinatal and Early Childhood: Awareness, Representation, Knowledge and Practice of Southern France Perinatal Health Professionals

Environmental Health in Perinatal and Early Childhood: Awareness, Representation, Knowledge and Practice of Southern France Perinatal Health Professionals

Perceptions, Practices, and Mother’s Willingness to Provide Meconium for Use in the Assessment of Environmental Exposures among Children in Mukono and Pallisa Districts, Uganda

Neurodevelopmental Disorders and Environmental Toxicants: Epigenetics as an Underlying Mechanism

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