Perspectives on digital microfluidics

Freire, Sergio L. S.

doi:10.1016/j.sna.2016.08.007

Cited by 51 publications

(33 citation statements)

References 157 publications

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“…The fabrication of the digital microfluidic is commonly performed on solid substrates, such as glass and polydimethylsiloxane. The bottom part contains the microchannel pattern while the upper part has the hydrophobic surface, and they are bound by using the electric field [87]. When the initial wettability of the microchannel surface is hydrophobic, the water droplet will form a sphere, however, when the electric field is applied, the wettability of the microchannel could be changed to hydrophilic.…”

Section: Principles Of Digital Microfluidicsmentioning

confidence: 99%

Microfluidics Era in Chemistry Field: A Review

et al. 2019

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By miniaturizing the reactor dimension, microfluidic devices are attracting world attention and starting the microfluidic era, especially in the chemistry field because they offer great advantages such as rapid processes, small amount of the required reagents, low risk, ease and accurate control, portable and possibility of online monitoring. Because of that, microfluidic devices have been massively investigated and applied for the real application of human life. This review summarizes the up-to-date microfluidic research works including continuous-flow, droplet-based, open-system, paper-based and digital microfluidic devices. The brief fabrication technique of those microfluidic devices, as well as their potential application for particles separation, solvent extraction, nanoparticle fabrication, qualitative and quantitative analysis, environmental monitoring, drug delivery, biochemical assay and so on, are discussed. Recent perspectives of the microfluidics as a lab-on-chip or micro total analysis system device and organ-on-chip are also introduced.

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Section: Principles Of Digital Microfluidicsmentioning

confidence: 99%

Microfluidics Era in Chemistry Field: A Review

et al. 2019

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“…Such this device has some important advantages: it is a completely electrical manner of inducing the transport and detecting the bio‐molecules; it does not require pumps, fluidic channels or bulky transducers; it is promising for the development of future all‐in‐one lab‐on‐chips. In the review of Freire , he gave a complete table of all advantages associated with using DMF in a variety of applications compared to other conventional methods (Table 2 ), showing an insightful future of studying DMF.…”

Section: Logic Fluidic Applications In Digital Microfluidicmentioning

confidence: 99%

Logic digital fluidic in miniaturized functional devices: Perspective to the next generation of microfluidic lab‐on‐chips

Zhang

Djeghlaf

et al. 2017

Electrophoresis

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Microfluidics has emerged following the quest for scale reduction inherent to micro- and nanotechnologies. By definition, microfluidics manipulates fluids in small channels with dimensions of tens to hundreds of micrometers. Recently, microfluidics has been greatly developed and its influence extends not only the domains of chemical synthesis, bioanalysis, and medical researches but also optics and information technology. In this review article, we will shortly discuss an enlightening analogy between electrons transport in electronics and fluids transport in microfluidic channels. This analogy helps to master transport and sorting. We will present some complex microfluidic devices showing that the analogy is going a long way off toward more complex components with impressive similarities between electronics and microfluidics. We will in particular explore the vast manifold of fluidic operations with passive and active fluidic components, respectively, as well as the associated mechanisms and corresponding applications. Finally, some relevant applications and an outlook will be cited and presented.

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“…A microfluídica [1][2][3] é uma linha de investigação científica crescente na última década e pode ser brevemente definida como o controle e estudo de fluídos em escala sub-milimétrica. Para isso é necessária a inserção de líquidos no interior de microcanais por pressão, capilaridade ou outras técnicas.O objetivo deste projeto é confeccionar microbombas de seringa utilizando impressão 3D para construção estrutural e o Arduino [4] para programá-las, de maneira a construir um sistema acoplado que controle a injeção de dois fluxos de maneira independente no interior de um microcanal.…”

Section: Introductionunclassified