Perspectives on the Molecular and Biological Implications of Tropoelastin in Human Tissue Elasticity

Abstract

The elasticity of a range of vertebrate and particularly human tissues depends on the dynamic and persistent protein elastin. This elasticity is diverse, and comprises skin, blood vessels, and lung, and is essential for tissue viability. Elastin is predominantly made by assembling tropoelastin, which is an asymmetric 20-nm-long protein molecule. This overview considers tropoelastin's molecular features and biological interactions in the context of its value in tissue repair.

Celebrating RACI and Academy of Science Awards

“…He has contributed a review on 'Perspectives on the Molecular and Biological Implications of Tropoelastin in Human Tissue Elasticity'. [4] Colin Jackson (ANU), winner of the Organic Division's 2015 Rennie Memorial Award, has presented a review with co-authors E. Sugrue, C. Hartley, and C. Scott on 'The Evolution of New Catalytic Mechanisms for Xenobiotic Hydrolysis in Bacterial Metalloenzymes'. [5] Lara Malins, formerly a Ph.D. student at the University of Sydney under Professor Richard Payne and now a post-doc at UC San Diego, won the RACI's 2015 Cornforth Award for the best Ph.D. thesis and has contributed a highlight on 'TransitionMetal Promoted Arylation: An Emerging Strategy for Protein Bioconjugation'.…”