Pertussis Infection in Adults With Persistent Cough

Wright, Seth W.; Edwards, Kathryn M.; Decker, Michael D.; Zeldin, Marie H.

doi:10.1001/jama.1995.03520370086042

Cited by 202 publications

(90 citation statements)

References 19 publications

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“…Thus, in adults with persistent cough, about 20% may have evidence of recent B. pertussis infection, certainly a large enough number to make this association one to consider in a differential diagnosis. As the patients have rather nonspecific symptoms, it would be difficult to distinguish them on clinical grounds [103]. This study and others referred to in the literature cited [103] would confirm the general impression that pertussis infection is on the rise.…”

Section: Bordetella Pertussissupporting

confidence: 64%

“…As the patients have rather nonspecific symptoms, it would be difficult to distinguish them on clinical grounds [103]. This study and others referred to in the literature cited [103] would confirm the general impression that pertussis infection is on the rise.…”

Section: Bordetella Pertussissupporting

confidence: 64%

“…These were compared with control subjects without respiratory complaints. This study [103] revealed important findings: (1) all but one subject had complete vaccination during childhood; (2) none had a positive culture for B. pertussis, and only in one was a DFA test positive; and (3) 16 subjects (or 21%) had a sufficiently high serologic titer on presentation or a rise found in the convalescent serum sample to qualify for the authors' diagnosis of recent infection. Thus, in adults with persistent cough, about 20% may have evidence of recent B. pertussis infection, certainly a large enough number to make this association one to consider in a differential diagnosis.…”

Section: Bordetella Pertussismentioning

confidence: 83%

“…The disease is being recognized increasingly in adolescents and adults. In fact, adults may be a reservoir of the disease and have a role in its transmission [103]. As with C. pneumoniae, a persistent cough might alert one to the diagnosis of pertussis.…”

Section: Bordetella Pertussismentioning

confidence: 99%

“…A study by Wright and colleagues [103] focused on persistent cough lasting 2 weeks or longer among adult patients evaluated in an emergency service and the prevalence of B. pertussis infection. Seventy-five adults, mean age 32 years + 10 years (S.D.…”

Section: Bordetella Pertussismentioning

confidence: 99%

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Respiratory infections: Community-acquired pneumonia and newer microbes

Reynolds

1996

Lung

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Respiratory infections, especially community-acquired forms of pneumonia (CAP), are challenging for clinicians because (1) a causative microorganism can only be found in about 50% of cases; (2) initial therapy, therefore, must be based on a probable or most likely etiology in the context of the patient's overall medical condition; and (3) new microbes or those considered previously as normal flora or less virulent forms seem responsible for some cases. It is important to be acquainted with new causes of infection which include Legionella species, Chlamydia pneumoniae, diphtheroids in certain instances (Corynebacterium pseudodiphtheriticum), and viruses such as the Hanta strains. Infections with Bordetella pertussis are increasing. However, the ever present and most common cause of CAP, Streptococcus pneumoniae, continues to present problems because of increasing antibiotic resistance, the high case fatality rate when bacteremia accompanies pneumonia, and the inability to give prophylactic immunization to all people with risk factors for this infection.

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Section: Bordetella Pertussissupporting

confidence: 64%

Section: Bordetella Pertussissupporting

confidence: 64%

Section: Bordetella Pertussismentioning

confidence: 83%

Section: Bordetella Pertussismentioning

confidence: 99%

Section: Bordetella Pertussismentioning

confidence: 99%

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Respiratory infections: Community-acquired pneumonia and newer microbes

Reynolds

1996

Lung

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Costs of Illness Due to Bordetella pertussis in Families

Lee

Pichichero²

2000

Archives of Family Medicine

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A Community-wide Pertussis Outbreak

Schafer

Gillette²,

Hedberg³

et al. 2006

Arch Intern Med

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Background: Pertussis incidence has increased in the United States since 1980, punctuated by outbreaks that involve adults and adolescents. We investigated a community-wide outbreak and studied risk factors among adults to identify prevention and control opportunities. Methods: We analyzed surveillance data, interviewed patients, visited outbreak sites, and conducted a casecontrol study of risk factors for first-in-household adult infection during a Jackson County, Oregon, outbreak in 2003. Results: In Jackson County, 135 pertussis cases were reported; the incidence was 71 per 100 000 population compared with 0 to 1 per 100 000 population from 1995 through 2001. Case investigations identified 2658 close contacts (19.7 per case); 1050 (40%) received antibiotic prophylaxis. Older children and adolescents (aged 10-17 years) and adults (aged Ն18 years) accounted for 67% of cases. Five infants were hospitalized (192 hospitalizations per 100 000 infants) compared with 18 in the re

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Pertussis Infection in Adults With Persistent Cough

Abstract: Pertussis is a common cause of persistent cough in adults and should be considered in the differential diagnosis. Clinical symptoms, pertussis culture, direct fluorescent antibody testing, and lymphocytosis are of limited value in making the diagnosis.

Cited by 202 publications

References 19 publications

Respiratory infections: Community-acquired pneumonia and newer microbes

Respiratory infections: Community-acquired pneumonia and newer microbes

Costs of Illness Due to Bordetella pertussis in Families

A Community-wide Pertussis Outbreak

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