Pertussis: New preventive strategies for an old disease

Mattia, Greta Di; Nicolai, Ambra; Frassanito, Antonella; Petrarca, Laura; Nenna, Raffaella

doi:10.1016/j.prrv.2018.03.011

Cited by 21 publications

(31 citation statements)

References 68 publications

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“…Fourth, previous publication has found that young infants accounted for the large proportion of the infected people in Chongqing 12,44 , this may be due to the fact that most young infants at the year of below 3 months were not vaccinated the DTwP vaccination, and the rapid decay of the antibodies to pertussis toxin (PT) and filamentous haemagglutinin (FHA) in infant sera derived from their mothers make infants susceptible to B. pertussis 49,50 . Fifth, prior studies reported that new B. pertussis strains different from that included in the present vaccines have emerged 47,51 , which may have effect on the manifest rebound of pertussis infections. Sixth, a recent research found that the proportion of the reported pertussis cases aged 1-5 and over 5 years have increased about 4 folds and the proportion aged 3-12 months reduced from 70.59 to 58.39% from 2013 to 2018, respectively, in Chongqing, which can be ascribed to the unqualified vaccine quality 44,52 .…”

Section: Discussionmentioning

confidence: 96%

“…Third, the traditional diphtheria, tetanus and whole-cell pertussis vaccine (DTwP) has been replaced by the combined diphtheria, tetanus and acellular pertussis vaccine (DTaP) in 2010, and yet there may be different efficacies against pathogenic infection between them, this may result in the adaptation or waning after vaccination to the natural or vaccine immunity 12 , 45 , 46 . It has been demonstrated that there is a protective effect of pertussis vaccine during the period of around 4–12 years 47 , 48 . According to the immunization schedule of pertussis in China 11 , it appeared that this situation accounted well for the increased numbers in adolescents and adults in temporality over the last years 44 .…”

Section: Discussionmentioning

confidence: 99%

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The long-term effects of meteorological parameters on pertussis infections in Chongqing, China, 2004–2018

Wang

Ren

et al. 2020

Sci Rep

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Evidence on the long-term influence of climatic variables on pertussis is limited. This study aims to explore the long-term quantitative relationship between weather variability and pertussis. Data on the monthly number of pertussis cases and weather parameters in Chongqing in the period of 2004–2018 were collected. Then, we used a negative binomial multivariable regression model and cointegration testing to examine the association of variations in monthly meteorological parameters and pertussis. Descriptive statistics exhibited that the pertussis incidence rose from 0.251 per 100,000 people in 2004 to 3.661 per 100,000 persons in 2018, and pertussis was a seasonal illness, peaked in spring and summer. The results from the regression model that allowed for the long-term trends, seasonality, autoregression, and delayed effects after correcting for overdispersion showed that a 1 hPa increment in the delayed one-month air pressure contributed to a 3.559% (95% CI 0.746–6.293%) reduction in the monthly number of pertussis cases; a 10 mm increment in the monthly aggregate precipitation, a 1 °C increment in the monthly average temperature, and a 1 m/s increment in the monthly average wind velocity resulted in 3.641% (95% CI 0.960–6.330%), 19.496% (95% CI 2.368–39.490%), and 3.812 (95% CI 1.243–11.690)-fold increases in the monthly number of pertussis cases, respectively. The roles of the mentioned weather parameters in the transmission of pertussis were also evidenced by a sensitivity analysis. The cointegration testing suggested a significant value among variables. Climatic factors, particularly monthly temperature, precipitation, air pressure, and wind velocity, play a role in the transmission of pertussis. This finding will be of great help in understanding the epidemic trends of pertussis in the future, and weather variability should be taken into account in the prevention and control of pertussis.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

The long-term effects of meteorological parameters on pertussis infections in Chongqing, China, 2004–2018

Wang

Ren

et al. 2020

Sci Rep

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“…Thirdly, there are various efficacies against pathogenic infection between whole cell and acellular vaccine, which may conduce to the adaptation or waning of pathogens to natural or vaccine immunity[33]. Evidence stemming from a slice of literature has proved that the provision of pertussis vaccine can function as precaution against causative agents with approximately 4–12 years, and the serum-specific antibody levels start to decline within 9 months exposed to antigen[8, 34]. Based on the vaccination procedure of pertussis in China[12], this situation exactly matches in temporality the fact that the infections in adolescents and adults have recently been in the growing notifications[10–12, 35, 36].…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, the past decade has witnessed a growing tendency for the incidence of pertussis in many places of the world, such as America, France, Germany, India, Canada, China and Australia and so on[6, 7]. Of these countries, outbreaks are frequently observed as well with a circle of every 2 to 5 years[8]. As such resurgence of pertussis incidence, this disease has caused wide public concern and is still viewed as a major public health issue in the world.…”

Section: Introductionmentioning

confidence: 99%

Time series modeling of pertussis incidence in China from 2004 to 2018 with a novel wavelet based SARIMA-NAR hybrid model

Wang

et al. 2018

PLoS ONE

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BackgroundIt is a daunting task to discontinue pertussis completely in China owing to its growing increase in the incidence. While basic to any formulation of prevention and control measures is early response for future epidemic trends. Discrete wavelet transform(DWT) has been emerged as a powerful tool in decomposing time series into different constituents, which facilitates better improvement in prediction accuracy. Thus we aim to integrate modeling approaches as a decision-making supportive tool for formulating health resources.MethodsWe constructed a novel hybrid method based on the pertussis morbidity cases from January 2004 to May 2018 in China, where the approximations and details decomposed by DWT were forecasted by a seasonal autoregressive integrated moving average (SARIMA) and nonlinear autoregressive network (NAR), respectively. Then, the obtained values were aggregated as the final results predicted by the combined model. Finally, the performance was compared with the SARIMA, NAR and traditional SARIMA-NAR techniques.ResultsThe hybrid technique at level 2 of db2 wavelet including a SARIMA(0,1,3)(1,0,0)12modelfor the approximation-forecasting and NAR model with 12 hidden units and 4 delays for the detail d1-forecasting, along with another NAR model with 11 hidden units and 5 delays for the detail d2-forecasting notably outperformed other wavelets, SARIMA, NAR and traditional SARIMA-NAR techniques in terms of the mean square error, root mean square error, mean absolute error and mean absolute percentage error. Descriptive statistics exhibited that a substantial rise was observed in the notifications from 2013 to 2018, and there was an apparent seasonality with summer peak. Moreover, the trend was projected to continue upwards in the near future.ConclusionsThis hybrid approach has an outstanding ability to improve the prediction accuracy relative to the others, which can be of great help in the prevention of pertussis. Besides, under current trend of pertussis morbidity, it is required to urgently address strategically within the proper policy adopted.

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“…Since maternal pertussis vaccination is a highly effective, safe and cost-effective intervention to prevent pertussis in newborn babies, many countries recommend pertussis vaccination for pregnant women [6][7][8]. However, regardless of the general public and individual health benefits of the maternal pertussis vaccine, in various countries which provide maternal pertussis vaccination for pregnant women, health care professionals (HCPs) and governments are confronted with parents' vaccine hesitancy and lower vaccine uptake among pregnant women than expected [9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Decision-making on maternal pertussis vaccination among women in a vaccine-hesitant religious group: Stages and needs

et al. 2020

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Introduction As of December 2019, pregnant women in the Netherlands are offered pertussis vaccination to protect their newborn infant against pertussis infection. However, the manner in which pregnant women decide about this maternal pertussis vaccination is largely unknown. The aim of this study is to gain insight into the decision-making process regarding maternal pertussis vaccination, and to explore the related needs among the vaccine-hesitant subgroup of orthodox Protestant women. Methods Charmaz’s grounded theory approach was used to develop a decision-making framework. To construct this framework we used an explorative multimethod approach in which in-depth interviews and online focus groups were supplemented by a literature search and research group meetings. This study was carried out in a hypothetical situation since the maternal pertussis vaccination had yet to be implemented in the Dutch immunisation programme at the time of the study. Results Twenty-five orthodox Protestant women participated in an interview, an online focus group, or in both. The findings of this study resulted in a decision-making framework that included three stages of decision-making; an Orientation stage, a value-based Deliberation stage, and Final decision stage. The Orientation stage included the needs for decision-making categorised into Information needs and Conversation needs. Women indicated that -if they were to receive sufficient time for Orientation and Deliberation- they would be able to reach the stage of Final decision. Conclusion The decision-making framework resulting from our findings can be used by health care professionals to provide women with information and consultation in the decision-making process. Future studies should investigate whether the stages of and needs for decision-making can be found across other vaccine-hesitant subgroups and vaccinations.

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Pertussis: New preventive strategies for an old disease

Cited by 21 publications

References 68 publications

The long-term effects of meteorological parameters on pertussis infections in Chongqing, China, 2004–2018

The long-term effects of meteorological parameters on pertussis infections in Chongqing, China, 2004–2018

Time series modeling of pertussis incidence in China from 2004 to 2018 with a novel wavelet based SARIMA-NAR hybrid model

Decision-making on maternal pertussis vaccination among women in a vaccine-hesitant religious group: Stages and needs

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