Pesticide-related poison center exposures in children and adolescents aged ≤19 years in Texas, 2000–2013

Trueblood, Amber B.; Forrester, Mathias B.; Han, Daikwon; Shipp, Eva M.; Cizmas, Leslie

doi:10.1080/15563650.2016.1201676

Cited by 9 publications

(8 citation statements)

References 9 publications

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“…Our findings are in agreement with these epidemiological reports. Taking into consideration that pyrethroids were commonly detected in children and adolescents, this raises the concern that pyrethroid exposure may present a serious threat to children's health.…”

Section: Discussionmentioning

confidence: 99%

Cis -bifenthrin induces immunotoxicity in adolescent male C57BL/6 mice

Wang

Gao

et al. 2017

Environmental Toxicology

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Bifenthrin (BF) is an important synthetic pyrethroid. Previous studies have demonstrated that cis-BF exhibits toxic effects on development, the neurological, reproductive and endocrine system. In this study, we evaluated the immunotoxicity caused by cis-BF in adolescent male C57BL/6 mice. Mice were exposed orally to 0, 5, 10, and 20 mg/kg/d for 3 weeks. The results showed that body weight, spleen weight, and splenic cellularity decreased in mice exposed to 20 mg/kg/d cis-BF. Additionally, we found that the mRNA levels of the pro-inflammatory factors IL-1β, IL-6, CXCL-1, and TNF-α, in peritoneal macrophages, the spleen, and the thymus were inhibited in the cis-BF-treated groups. Moreover, MTT assays demonstrated that cis-BF inhibited splenocyte proliferation stimulated by LPS or Con A, as well as the secretion of IFN-γ on Con A stimulation. Collectively, the results of this study suggest that exposure to cis-BF has the potential to induce immunotoxicity in adolescent male C57BL/6 mice.

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Section: Discussionmentioning

confidence: 99%

Cis -bifenthrin induces immunotoxicity in adolescent male C57BL/6 mice

Wang

Gao

et al. 2017

Environmental Toxicology

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“…For this study, pesticide-related poison center exposures were defined as all calls with a pesticide reported as an exposure, which was defined based on the reported generic Poisiondex codes (a database that contains product information used to group products). The codes used to define pesticide-related exposures had been previously published [ 8 ]. Poison center data included in this study were the frequency of unintentional pesticide-related poison center exposures by caller county, for three American Association of Poison Control Centers (AAPCC) age groupings for children and adolescents (children ≤5 years, children 6-12 years, and adolescents 13-19 years).…”

Section: Methodsmentioning

confidence: 99%

Exploring Demographic and Environmental Factors Related to Unintentional Pesticide Poisonings in Children and Adolescents in Texas

Trueblood

Han

Shipp

et al. 2018

Environ Health Toxicol

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There is limited literature on the frequency and distribution of pesticide exposures, specifically with respect to demographic and environmental factors in the United States. The purpose of this exploratory study was to investigate geographic trends and factors associated with unintentional pesticide exposures in children and adolescents in Texas. The study used an ecological design with secondary data. A spatial scan statistic, based on a Poisson regression model, was employed to identify spatial clusters of unintentional pesticide-related poison center exposures. Next, logistic regression models were constructed to identify potential demographic and environmental factors associated with unintentional pesticide-related poison center exposures. There were 59,477 unintentional pesticide-related poison center exposures from 2000 to 2013. The spatial scan statistic found a change in the number of counties in the identified clusters (e.g. , aggregation of counties with higher than expected exposures) for two time periods (2000-2006; 2007-2013). Based on the logistic regression models, factors associated with unintentional pesticide-related poison center exposures were percent black or African American population, year structure built, and percent moved in the past 12 months. In conclusion, this study found certain demographic and environmental factors may be associated with unintentional pesticide-related poison center exposures. Through understanding trends and associated factors, public health professionals can design interventions for populations at higher risk of pesticide exposures. This study also supports the use of spatial methods being utilized to expand upon current analysis of poison center data. Future research should confirm and build upon these findings.

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“…Vidi et al (179) reported a significant association between bifenthrin, cypermethrin, deltamethrin, cis-and trans-permethrin and DNA damage in the hair of residentially exposed children in farmer households. An observational study using data from poison control centres reported that the second most common pesticide group by exposure frequency were pyrethroids, and children aged ≤5 years were the group most at risk of exposure (180). Campos et al (181) suggested an association between pyrethroid exposure and mental disorders.…”

Section: Human Exposure To Pyrethroidsmentioning

confidence: 99%

Non-target toxicity of novel insecticides

Mužinić

Želježić

2018

Archives of Industrial Hygiene and Toxicology

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Humans have used insecticides since ancient times. The spectrum and potency of available insecticidal substances has greatly expanded since the industrial revolution, resulting in widespread use and unforeseen levels of synthetic chemicals in the environment. Concerns about the toxic effects of these new chemicals on non-target species became public soon after their appearance, which eventually led to the restrictions of use. At the same time, new, more environmentally-friendly insecticides have been developed, based on naturally occurring chemicals, such as pyrethroids (derivatives of pyrethrin), neonicotinoids (derivatives of nicotine), and insecticides based on the neem tree vegetable oil (Azadirachta indica), predominantly azadirachtin. Although these new substances are more selective toward pest insects, they can still target other organisms. Neonicotinoids, for example, have been implicated in the decline of the bee population worldwide. This review summarises recent literature published on non-target toxicity of neonicotinoids, pyrethroids, and neem-based insecticidal substances, with a special emphasis on neonicotinoid toxicity in honeybees. We also touch upon the effects of pesticide combinations and documented human exposure to these substances.

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Pesticide-related poison center exposures in children and adolescents aged ≤19 years in Texas, 2000–2013

Abstract: Through characterizing pesticide-related poison center exposures, future interventions can be designed to address groups with higher prevalence of exposure.

Cited by 9 publications

References 9 publications

Cis -bifenthrin induces immunotoxicity in adolescent male C57BL/6 mice

Cis -bifenthrin induces immunotoxicity in adolescent male C57BL/6 mice

Exploring Demographic and Environmental Factors Related to Unintentional Pesticide Poisonings in Children and Adolescents in Texas

Non-target toxicity of novel insecticides

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