Pesticide Residues and Heavy Metals in Lake Victoria Nile Perch, Lates niloticus, Belly Flap Oil

Ogwok, Patrick; Muyonga, John H.; Sserunjogi, M.L.

doi:10.1007/s00128-009-9668-x

Cited by 32 publications

(20 citation statements)

References 15 publications

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“…Bakyaita, 2010). Lead and Hg have been detected in African fish eagles, Marabou storks and Nile perch (Hollamby et al, 2004;Ogwok, Muyonga & Sserunjogi, 2009). Further, high levels of Pb and Cd have been reported in milk from farms in Wakiso district (Nyakairu, Muhwezi & Biryomumaisho, 2011).…”

Section: Introductionmentioning

confidence: 99%

Human Health Risk Assessment of Heavy Metals in Kampala (Uganda) Drinking Water

Bamuwamye¹,

Ogwok²,

Tumuhairwe³

et al. 2017

JFR

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Levels of aluminium, arsenic, cadmium, chromium, copper, iron, mercury, manganese, nickel, lead and zinc in tap water, groundwater-fed protected spring and bottled water were determined. The cancer and non-cancer risks associated with ingestion of heavy metals (HM) were also assessed for both children and adults. Forty seven water samples obtained from five divisions of Kampala city were analyzed using atomic absorption spectrophotometry. Cancer and non-cancer risks were determined using incremental lifetime cancer risk (ILCR) and non-carcinogenic hazard quotient (HQ), respectively. Lead content was higher than permissible limits (PL) according to East African Standard, World Health Organization, European Union and United States Environmental Protection Agency (USEPA). Arsenic showed minor exceedances above guideline values in tap water and groundwater-fed protected spring, whereas mercury, manganese and nickel were higher than PL. Levels of aluminium, cadmium, chromium, copper, iron, and zinc were below the PL. The lifetime risk of developing cancer through the oral route was greater than the USEPA acceptable level for both children and adults, revealing that exposure to HM in drinking water posed an unacceptable potential cancer risk. Arsenic contributed ca. 90% of the ILCR in tap water and groundwater-fed protected spring. The combined non-cancer risk of the HM expressed as hazard index (HI) was greater than one, with values for children being higher than those for adults. Lead contribution towards HI was in all cases above 90%. These results demonstrate the presence of alarming non-cancer risks for children.

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Section: Introductionmentioning

confidence: 99%

Human Health Risk Assessment of Heavy Metals in Kampala (Uganda) Drinking Water

Bamuwamye¹,

Ogwok²,

Tumuhairwe³

et al. 2017

JFR

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“…Dieldrin is highly persistent in the environment and its absence could mean that no previous application was carried out in Mukono. In spite of the reported use of the pesticide, residual levels of dieldrin are still reported as being below LOD in fish, African fish eagle and marabou stork from Lake Victoria basin [15,16]. Low levels of dieldrin residue in the Lake Victoria environment are explained by the current reduced usage in contrast with former application against banana weevils [17].…”

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confidence: 84%

“…Residual levels of DDT and its metabolites in carrots may be a result of drift or water runoff from indoor application. Trace levels of DDT metabolite, just like other organochlorine pesticides, were previously detected in fish, birds and animal products around Lake Victoria basin [15][16][17].…”

mentioning

confidence: 97%

Organochlorine pesticide residues in skin, flesh and whole carrots (Daucus carota) from markets around Lake Victoria basin, Uganda

Nannyonga

Kiremire

Ogwok

et al. 2013

International Journal of Environmental Studies

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“…Pesticide is a double edged sword, which plays very important roles in increasing crop production and income, but it also causes some negative effects, such as environmental pollutions [1], [2], homicidal and suicidal accident [3], cancer and other diseases [4]. Among the total amount of pesticide in china, more than 40% of them are chiral [5], and this ratio is increasing as more and more complex structures are being developed.…”

Section: Introductionmentioning

confidence: 99%

Enantioselective Metabolism of Quizalofop-Ethyl in Rat

et al. 2014

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The pharmacokinetic and distribution of the enantiomers of quizalofop-ethyl and its metabolite quizalofop-acid were studied in Sprague-Dawley male rats. The two pairs of enantiomers were determined using a validated chiral high-performance liquid chromatography method. Animals were administered quizalofop-ethyl at 10 mg kg−1 orally and intravenously. It was found high concentration of quizalofop-acid in the blood and tissues by both intragastric and intravenous administration, and quizalofop-ethyl could not be detected through the whole study which indicated a quick metabolism of quizalofop-ethyl to quizalofop-acid in vivo. In almost all the samples, the concentrations of (+)-quizalofop-acid exceeded those of (−)-quizalofop-acid. Quizalofop-acid could still be detected in the samples even at 120 h except in brain due to the function of blood-brain barrier. Based on a rough calculation, about 8.77% and 2.16% of quizalofop-acid were excreted through urine and feces after intragastric administration. The oral bioavailability of (+)-quizalofop-acid and (−)-quizalofop-acid were 72.8% and 83.6%.

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Pesticide Residues and Heavy Metals in Lake Victoria Nile Perch, Lates niloticus, Belly Flap Oil

Cited by 32 publications

References 15 publications

Human Health Risk Assessment of Heavy Metals in Kampala (Uganda) Drinking Water

Human Health Risk Assessment of Heavy Metals in Kampala (Uganda) Drinking Water

Organochlorine pesticide residues in skin, flesh and whole carrots (Daucus carota) from markets around Lake Victoria basin, Uganda

Enantioselective Metabolism of Quizalofop-Ethyl in Rat

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