This paper compares detections and concentrations of specific organophosphate, bis-dithiocarbamate, and pyrethroid insecticide urinary metabolites among Latino male farmworkers and non-farmworkers in North Carolina. Data are from interviews and urine samples collected in 2012 and 2013. Farmworkers and non-farmworkers frequently had detections for OP and pyrethroid pesticide urinary metabolites. Detections of bis-dithiocarbamate urinary metabolites were less frequent, but substantial among the non-farmworkers. The concentrations of organophosphate, bis-dithiocarbamate, and pyrethroid pesticide urinary metabolites were high for farmworkers and non-farmworkers compared to National Health and Nutrition Examination Survey results. Pesticide urinary metabolite detection was not associated with occupation in non-farmworkers. Research for reducing pesticide exposure among farmworkers remains important; research is also needed to determine pesticide exposure pathways among Latino non-farmworkers.