Presently chemical plant protection products are an inseparable part of agriculture. They have not only their main purpose of plant assistance, but they also have the potential risk of negative impact on biocenosis species (birds, bees, soil microflora, algae, etc.) and the human body and its health respectively. The purpose of our study was to aggregate data on the existing legal framework of plant protection products in Ukraine and assess their ecology and hygiene monitoring. For analysis of the plant chemical protection, we used as the basic documents the regulatory framework of domestic legislation in toxicological and hygiene, ecology assessment, and ecology and hygiene monitoring domains. Currently, many laws and legal acts regulate the use of pesticides by state and private agricultural farms in Ukraine. This number of documents covers not only pre-registration studies of pesticides but also their post-registration monitoring in the environment. The key entities that control potential negative risks of these products through the regulations are the State Emergency Service, Ministry of Environmental Protection, Ministry of Health, Ministry of Housing and Communal Services, Ministry of Agriculture Policy, State Agency of Water Resources, State Committee of Land Resources, State Agency of the Forest Resources. However, the impact of xenobiotics on non-target species of the ecosystem is currently quite underestimated. The decline in biodiversity directly depends on the condition of the environment and the negative impact on it. Instances of acute oral, inhalation, or dermal poisoning of birds, bees, and aquatic invertebrates with pesticides are quite common and among the factors that affect public health. That is why ecology and hygiene monitoring is essential in line with the assessment of the risks of the inappropriate release of pesticides. These should be treated as a critical component of managing environmental sustainability and safety for public health. The implementation of global approaches to monitoring and controlling the post- registration impact of pesticides on the ecology and hygiene in Ukraine can also take into account the far-reaching consequences of their negative impact, accumulation, and environmental pollution. As a result, this will help to avoid adverse impacts on animal, insect, and bird populations, as well as human health.
