PET and SPECT performance of the Siemens HD3 e.cam/sup duet//spl reg/ : a 1" Na(I) hybrid camera

Morin, Olivier; Celler, Anna; Rempel, T.D.; Belzberg, Allan S.; Carhart, C.

doi:10.1109/nssmic.2002.1239606

Cited by 2 publications

(2 citation statements)

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“…This hybrid SPECT/ PET system employs 1.0-inch-thick segmented NaI crystals and 7.6 cm-long slat collimators. Operating in 2D mode with 18 F (similar to 2D PET imaging), the sensitivity was roughly 500 cps/MBq, corresponding to 18,500 cps/mCi (Sossi et al 2003). This represents a sensitivity difference of about a factor of 10,000:1.…”

Section: Discussionmentioning

confidence: 99%

“…One approach that was pursued in the past involved modifications of the gamma camera energy range combined with coincidence electronics, serving as an alternative to dedicated PET systems (Miyaoka et al 1995, Patton and Turkington 1999, Sossi et al 2003. While the performance of these dual-head coincidence cameras were lower compared to dedicated PET systems, they served as a cost-effective approach to both nuclear medicine and PET imaging (Nellemann et al 1995, Kunze et al 2000, Schelper et al 2006.…”

Section: Introductionmentioning

confidence: 99%

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A Monte Carlo simulation of coincidence detection and imaging of gamma-ray cascades with a scintillation camera

Pahlka

Kappadath

Mawlawi

2018

Biomed. Phys. Eng. Express

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Several radionuclei used in nuclear medicine decay through the emission of cascaded gamma-rays. These successively-emitted gamma-rays could potentially be detected in coincidence and then be used to create coincident event-based images. While several groups have considered various ways to leverage the gamma-ray cascade to produce images, the concept of producing images using cascaded gammarays in coincidence with a dual-head gamma camera has not been previously explored in detail. Given that current dual-head gamma cameras cannot be configured in coincidence mode, the purpose of this work was to explore this concept with In-111 using a Monte Carlo simulation. First, GEANT4 was used to model a dual-head gamma camera and to simulate the decay of the nucleus. The model was then validated using planar data from a physical scanner. The validated model was then used to simulate a point source of In-111 located at the camera isocenter to evaluate the true coincidence efficiency with the detectors oriented at 90 degrees. The noise-equivalent-count-rate (NECR) as a function of timing window resolution was computed for different source activities. A simple reconstruction algorithm was then used to produce coincidence-based images from sources in various configurations. The coincident gamma-ray detection efficiency for a single point source in air with the detector heads oriented at 90 degrees was found to be 6×10 −8 , independent of the source-to-detector distance. The time window resolution for the maximum NECR ranged between 200 and 500 ns, dependent on source activity. The algorithm could produce images over a range of timing window resolutions, with varying levels of reconstruction artifacts. Images produced from a small acrylic phantom showed that scattered events produced small degradations in resolution and contrast-to-noise ratios. This work described the conditions under which images based on coincident events from In-111 could be created using a dualhead gamma camera, assuming appropriate electronics modifications.

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Section: Discussionmentioning

confidence: 99%