PET-CT-Bildgebung bei Kopf-Hals-Tumoren

Abstract

Fused PET/CT imaging with [F18]-FDG and native CT-scanning enables accurate diagnosis in 93% of lesions and 90% of patients with head and neck oncology.

Combined FDG-PET/CT for the detection of unknown primary tumors: systematic review and meta-analysis

“…Reviewing titles and abstracts from Embase revealed 17 articles potentially eligible for inclusion, of which 15 were all already identified by the PubMed/MEDLINE search. Thus, 19 studies [12–30] remained for possible inclusion and were retrieved in full text version. Screening of the references of these 19 articles did not bring up new articles.…”

“…Screening of the references of these 19 articles did not bring up new articles. After reviewing the full article, two articles [17, 19] were excluded because a part of the study population underwent FDG-PET alone and was not separately analyzed from patients undergoing FDG-PET/CT, two articles [25, 30] were excluded because sensitivity and specificity for primary tumor detection could not be calculated, one article [28] was excluded because it did not separately analyze patients with CUP, one article [21] was excluded because fewer than ten patients with CUP were included, one article [23] was excluded because it was an editorial, and one article [24] was excluded because the same data were used in a later study. Eventually, 11 studies [12–16, 18, 20, 22, 26, 27, 29], comprising a total sample size of 433 patients with CUP, met all inclusion and exclusion criteria, and they were included in this systematic review.…”

Cardiac Metastasis in a Patient with Head and Neck Cancer: A Case Report and Review of the Literature

“…Current National Comprehensive Cancer Network (NCCN) guidelines do not recommend the use of routine follow-up imaging unless clinically indicated and no evidence to demonstrate a benefit of surveillance imaging after 6 months [11]. However, multiple case reports have reported that the use of PET/CT may lead to improved accuracy and earlier detection of cardiac metastases in patients with head and neck cancer [4, 12–15]. Some studies have suggested that routine ECG may have a diagnostic value, but findings are often nonspecific, and further confirmation with imaging would be required [15–17].…”

Current oncologic concepts and emerging techniques for imaging of head and neck squamous cell cancer

“…Whereas PET did not have the status of an essential diagnostic requirement in the “guidelines for tumors of the upper aerodigestive tract 2003” [45], to date there has been a paradigm shift. In the meantime, several studies admit the importance of 18F-FDG PET-CT for nodal staging of head and neck squamous cell carcinoma and the cervical CUP syndrome [37], [38], [39], [46], [47], [48]. 18F-FDG PET-CT can provide evidence of a second tumor during staging, considering the fact that in patients with HNSCC there is a 10 to 30-fold higher risk than in the general population for the development of secondary tumors outside the head and neck region.…”