Peterson Olefination

Abstract

The two‐step synthesis of olefin involving the addition of an α‐silyl carbanion to a carbonyl compound to form β‐silyl alcohol and the elimination of silol is generally known as the Peterson olefination. This reaction has many advantages. This reaction has been modified by the use of an α‐silyl selenoacetamide to generate E ‐olefins. Furthermore, an asymmetric version of this reaction has been developed by the use of an external chiral tridentate amino diether as a chiral ligand. This reaction has been generally applied in the preparation of olefins.