The Carboniferous is an important period for understanding tectonic evolutionary history and subduction processes of Chinese western Tianshan orogen. Here, we present results of petrologic, geochemical, and in situ LA-ICP-MS zircon U-Pb and Hf isotope data from an Early Carboniferous mafic dike-syenitic granite association in Atengtao Mountain, Yili Block, aiming to constrain their ages and petrogenesis and tectonic significance. Zircon U-Pb dating results reveal that the mafic dikes and syenitic granites were coevally emplaced at ca. 345-349 Ma. Geochemically, the mafic dikes contain high MgO, Nb, TiO 2 , and Ta contents, low SiO 2 contents, and high Na 2 O/K 2 O ratios, showing Nb-enriched affinities. Additionally, they are enriched in LILEs, relatively depleted in HFSEs, and positive εHf (t) values (+1.2 to +8.7), likely representing melts derived from partial melting of a depleted mantle wedge metasomatized by subducted slab-derived fluids, with minor involvement of asthenospheric components. Compared with mafic dikes, the coeval syenitic granites display calc-alkaline I-type features and have high SiO 2 , Al 2 O 3 , and low MgO, Mg # (<40), Ni, and Cr contents, considered to have been derived from the reworking of the Precambrian basementwith an input of mantle-derived components. These mafic dike-syenitic granite associations likely formed in an arc-related setting rather than postcollision or mantle plume setting. In addition, pronouncedly higher zircon saturation temperature of the syenitic granites, compared with the coeval I-type granitoids from western Tianshan, imply the occurrence of a thermal anomaly in this period (ca. 345 Ma). With these studied results, together with previously published data, we argue that a slab breakoff model was likely responsible for the mafic dike-syenitic granite association, and related rocks, in the western Yili Block during Early Carboniferous.