2012
DOI: 10.4269/ajtmh.2012.11-0797
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PFE0565w, a Plasmodium falciparum Protein Expressed in Salivary Gland Sporozoites

Abstract: Abstract. Because malaria is still a significant problem worldwide, additional control methods need to be developed. The Plasmodium sporozoite is a good target for control measures because it displays dual infectivity for both mosquito and vertebrate host tissues. The Plasmodium falciparum gene, PFE0565w, was chosen as a candidate for study based on data from PlasmoDB, the Plasmodium database, indicating that it is expressed both at the transcriptional and protein levels in sporozoites, likely encodes a putati… Show more

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Cited by 2 publications
(10 citation statements)
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“…Anopheles stephensi were reared as previously described [7,8] and used for maintaining the P. falciparum life cycle and parasite transmission. The P. falciparum NF54 strain and 3D7HT-GFP parasites (a constitutively green fluorescent protein (GFP)-expressing parasite line) were maintained according to a standard protocol [8,9] and used for mosquito-parasite infections.…”
Section: Methodsmentioning
confidence: 99%
See 4 more Smart Citations
“…Anopheles stephensi were reared as previously described [7,8] and used for maintaining the P. falciparum life cycle and parasite transmission. The P. falciparum NF54 strain and 3D7HT-GFP parasites (a constitutively green fluorescent protein (GFP)-expressing parasite line) were maintained according to a standard protocol [8,9] and used for mosquito-parasite infections.…”
Section: Methodsmentioning
confidence: 99%
“…The P. falciparum NF54 strain and 3D7HT-GFP parasites (a constitutively green fluorescent protein (GFP)-expressing parasite line) were maintained according to a standard protocol [8,9] and used for mosquito-parasite infections. Mosquito parasite transmission studies also were performed according to standard protocol [8].…”
Section: Methodsmentioning
confidence: 99%
See 3 more Smart Citations