Pfeiffer Syndrome Type 1: A Case Report

GE, Kocak; Koray, Meltem

doi:10.19070/2377-8075-18000122

Cited by 1 publication

(2 citation statements)

References 11 publications

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“…Six of the female patients had a history of hormone changes, including pregnancy, hormone therapy, and gynecological treatment. Two females developed MICRR during pregnancy (Chen et al, 2020;Ge & Wang, 2013), two experienced worsening of the MICRR after pregnancy (George & Miller, 1986;Liang et al, 2003), while two developed MICRR after hormone therapy or gynecological surgery (Kerr et al, 1970;Lydiatt et al, 1989), so we propose that the occurrence and progression of MICRR may be related to hormone changes in females. Deeb et al (2019) reported that one patient developed MICRR after denosumab discontinuation and proposed the "rebound effect hypothesis."…”

Section: Discussionmentioning

confidence: 93%

“…Functional studies have suggested that this mutation may inhibit IRF8 expression and weaken IRF8 protein function to promote osteoclasts generation at the transcription level and increase the risk for root resorption (Thumbigere-Math et al, 2019). In addition, MICRR or development of new lesions was observed in six female patients undergoing hormonal changes, including pregnancy, hormone therapy, or gynecological treatment (Chen et al, 2020;Ge & Wang, 2013;George & Miller, 1986;Kerr et al, 1970;Liang et al, 2003;Lydiatt et al, 1989), which indicates that hormonal changes in female patients may be related to MICRR.…”

Section: Predisposing Factorsmentioning

confidence: 99%

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Multiple idiopathic cervical root resorption: A systematic review

et al. 2022

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The current literature on multiple idiopathic cervical root resorption (MICRR), a rare and aggressive form of external root resorption, is limited to case reports and series. Therefore, we performed a systematic review of this condition. A comprehensive search of PubMed, Embase, Web of science, Cochrane Library, CNKI, and WANFANG was conducted using key terms relevant to MICRR, supplemented by a grey literature search. Risk of bias was assessed using Cochrane's and Joanna Briggs Institute's tools. A total of 36 studies with 47 cases were included. MICRR is more common among younger females and may be related to hormonal changes and denosumab use. Initially, the premolars are usually affected but all permanent teeth may eventually be involved. Cone‐beam computed tomography is recommended for diagnosis and assessment of resorptive lesions. The management is focused on complete removal and restoration of the resorptive tissue to maintain the tooth's structural integrity. However, MICRR usually has a poor prognosis. Due to its invasive and aggressive behavior, MICRR requires greater attention.

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