PGT-A improved singleton live birth rate among all age groups of women who underwent elective single blastocyst transfer: a single-centre retrospective study

Zheng, Zetong; Tan, Jia-Yi; Chen, Lin; Liu, Simin; Zhou, Canquan; Li, Yubin

doi:10.1007/s10815-023-02775-2

J Assist Reprod Genet

2023

DOI: 10.1007/s10815-023-02775-2

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PGT-A improved singleton live birth rate among all age groups of women who underwent elective single blastocyst transfer: a single-centre retrospective study

Zetong Zheng

Jia-Yi Tan

Lin Chen

et al.

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Cited by 3 publications

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Beyond appearance: Can morphologically low‐grade euploid blastocysts yield successful pregnancies?

Suzuki,

Ishida,

Yoshioka

et al. 2024

Reprod Medicine & Biology

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PurposeThe primary objective of this investigation is to evaluate how morphological quality affects the pregnancy outcomes in euploid embryos determined by preimplantation genetic testing for aneuploidies (PGT‐A). Concurrently, as a secondary objective, we aim to identify which specific aspects of morphological evaluation exert the most significant impact on these outcomes.MethodsA retrospective analysis of 451 single euploid embryo transfer cycles at our clinic was conducted. Embryos were evaluated based on the degree of blastocyst expansion, inner cell mass (ICM), trophectoderm (TE) morphology, and the day of blastocyst vitrification. Outcomes between morphologically low‐grade and high‐grade embryos were compared. Additionally, the study analyzed which morphological factors most influenced pregnancy outcomes.ResultsPregnancy outcomes were significantly lower in morphologically low‐grade blastocysts compared to high‐grade ones. Among the morphological evaluations, the ICM assessment was significantly associated with the live birth rate.ConclusionOur study indicates that the morphological quality of euploid embryos, particularly the evaluation of the ICM, plays a crucial role in IVF‐ET success.

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Beyond appearance: Can morphologically low‐grade euploid blastocysts yield successful pregnancies?

Suzuki,

Ishida,

Yoshioka

et al. 2024

Reprod Medicine & Biology

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Sociocultural imperatives for Singapore to permit preimplantation genetic testing-aneuploidy (PGT-A) despite uncertain results and ongoing controversy

Chin¹,

Sun

2023

J Assist Reprod Genet

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Success rates with preimplantation genetic testing for aneuploidy in good prognosis patients are dependent on age

Harris,

Acharya,

Unnithan

et al. 2024

Fertility and Sterility

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PGT-A improved singleton live birth rate among all age groups of women who underwent elective single blastocyst transfer: a single-centre retrospective study

Cited by 3 publications

References 39 publications

Beyond appearance: Can morphologically low‐grade euploid blastocysts yield successful pregnancies?

Beyond appearance: Can morphologically low‐grade euploid blastocysts yield successful pregnancies?

Sociocultural imperatives for Singapore to permit preimplantation genetic testing-aneuploidy (PGT-A) despite uncertain results and ongoing controversy

Success rates with preimplantation genetic testing for aneuploidy in good prognosis patients are dependent on age

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